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CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors

BACKGROUND: Expression of killer cell lectin-like receptor B1 (KLRB1), the gene encoding the cell surface molecule CD161, is associated with favorable prognosis in many cancers. CD161 is expressed by several lymphocyte populations, but its role and regulation on tumor-specific CD4+ T cells is unknow...

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Detalles Bibliográficos
Autores principales:	Duurland, Chantal L, Santegoets, Saskia J, Abdulrahman, Ziena, Loof, Nikki M, Sturm, Gregor, Wesselink, Tom H, Arens, Ramon, Boekestijn, Sanne, Ehsan, Ilina, van Poelgeest, Mariette I E, Finotello, Francesca, Hackl, Hubert, Trajanoski, Zlatko, ten Dijke, Peter, Braud, Veronique M, Welters, Marij J P, van der Burg, Sjoerd H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765066/ https://www.ncbi.nlm.nih.gov/pubmed/35039463 http://dx.doi.org/10.1136/jitc-2021-003995

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