Efficacy of pembrolizumab and comprehensive CD274/PD-L1 profiles in patients previously treated with chemoradiation therapy as radical treatment in bladder cancer

BACKGROUND: Chemoradiation therapy (CRT) has been increasingly reported as a possible alternative to total cystectomy (TC) for localized bladder cancer (BC). Pembrolizumab is the standard of care for platinum-refractory metastatic urothelial carcinoma, although it is unknown whether the efficacy of...

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Detalles Bibliográficos
Autores principales: Nishimura, Kazuki, Nishio, Kyosuke, Hirosuna, Kensuke, Komura, Kazumasa, Hayashi, Takuo, Fukuokaya, Wataru, Ura, Ayako, Uchimoto, Taizo, Nakamura, Ko, Fukushima, Tatsuo, Yano, Yusuke, Takahashi, Nobushige, Nakamori, Keita, Kinoshita, Shoko, Matsunaga, Tomohisa, Tsutsumi, Takeshi, Tsujino, Takuya, Taniguchi, Kohei, Tanaka, Tomohito, Uehara, Hirofumi, Takahara, Kiyoshi, Inamoto, Teruo, Hirose, Yoshinobu, Kimura, Takahiro, Egawa, Shin, Azuma, Haruhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765067/
https://www.ncbi.nlm.nih.gov/pubmed/35039462
http://dx.doi.org/10.1136/jitc-2021-003868

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