Regulating Expression of Mistranslating tRNAs by Readthrough RNA Polymerase II Transcription

[Image: see text] Transfer RNA (tRNA) variants that alter the genetic code increase protein diversity and have many applications in synthetic biology. Since the tRNA variants can cause a loss of proteostasis, regulating their expression is necessary to achieve high levels of novel protein. Mechanism...

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Detalles Bibliográficos
Autores principales: Berg, Matthew D., Isaacson, Joshua R., Cozma, Ecaterina, Genereaux, Julie, Lajoie, Patrick, Villén, Judit, Brandl, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765249/
https://www.ncbi.nlm.nih.gov/pubmed/34726901
http://dx.doi.org/10.1021/acssynbio.1c00461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765249/
https://www.ncbi.nlm.nih.gov/pubmed/34726901
http://dx.doi.org/10.1021/acssynbio.1c00461

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