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Regulating Expression of Mistranslating tRNAs by Readthrough RNA Polymerase II Transcription
[Image: see text] Transfer RNA (tRNA) variants that alter the genetic code increase protein diversity and have many applications in synthetic biology. Since the tRNA variants can cause a loss of proteostasis, regulating their expression is necessary to achieve high levels of novel protein. Mechanism...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765249/ https://www.ncbi.nlm.nih.gov/pubmed/34726901 http://dx.doi.org/10.1021/acssynbio.1c00461 |