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Understanding multiscale structure–property correlations in PVDF-HFP electrospun fiber membranes by SAXS and WAXS

Electrospinning is a versatile technique to produce nanofibrous membranes with applications in filtration, biosensing, biomedical and tissue engineering. The structural and therefore physical properties of electrospun fibers can be finely tuned by changing the electrospinning parameters. The large p...

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Autores principales: Maurya, Anjani K., Mias, Eloïse, Schoeller, Jean, Collings, Ines E., Rossi, René M., Dommann, Alex, Neels, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765355/
https://www.ncbi.nlm.nih.gov/pubmed/35178501
http://dx.doi.org/10.1039/d1na00503k
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author Maurya, Anjani K.
Mias, Eloïse
Schoeller, Jean
Collings, Ines E.
Rossi, René M.
Dommann, Alex
Neels, Antonia
author_facet Maurya, Anjani K.
Mias, Eloïse
Schoeller, Jean
Collings, Ines E.
Rossi, René M.
Dommann, Alex
Neels, Antonia
author_sort Maurya, Anjani K.
collection PubMed
description Electrospinning is a versatile technique to produce nanofibrous membranes with applications in filtration, biosensing, biomedical and tissue engineering. The structural and therefore physical properties of electrospun fibers can be finely tuned by changing the electrospinning parameters. The large parameter window makes it challenging to optimize the properties of fibers for a specific application. Therefore, a fundamental understanding of the multiscale structure of fibers and its correlation with their macroscopic behaviors is required for the design and production of systems with dedicated applications. In this study, we demonstrate that the properties of poly(vinylidene fluoride-co-hexafluoro propylene) (PVDF-HFP) electrospun fibers can be tuned by changing the rotating drum speed used as a collector during electrospinning. Indeed, with the help of multiscale characterization techniques such as scanning electron microscopy (SEM), small-angle X-ray scattering (SAXS), and wide-angle X-ray scattering (WAXS), we observe that increasing the rotating drum speed not only aligns the fibers but also induces polymeric chain rearrangements at the molecular scale. Such changes result in enhanced mechanical properties and an increase of the piezoelectric β-phase of the PVDF-HFP fiber membranes. We detect nanostructural deformation behaviors when the aligned fibrous membrane is uniaxially stretched along the fiber alignment direction, while an increase in the alignment of the fibers is observed for randomly aligned samples. This was analyzed by performing in situ SAXS measurements coupled with uniaxial tensile loading of the fibrous membranes along the fiber alignment direction. The present study shows that fibrous membranes can be produced with varying degrees of fiber orientation, piezoelectric β-phase content, and mechanical properties by controlling the speed of the rotating drum collector during the fiber production. Such aligned fiber membranes have potential applications for neural or musculoskeletal tissue engineering.
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spelling pubmed-87653552022-02-15 Understanding multiscale structure–property correlations in PVDF-HFP electrospun fiber membranes by SAXS and WAXS Maurya, Anjani K. Mias, Eloïse Schoeller, Jean Collings, Ines E. Rossi, René M. Dommann, Alex Neels, Antonia Nanoscale Adv Chemistry Electrospinning is a versatile technique to produce nanofibrous membranes with applications in filtration, biosensing, biomedical and tissue engineering. The structural and therefore physical properties of electrospun fibers can be finely tuned by changing the electrospinning parameters. The large parameter window makes it challenging to optimize the properties of fibers for a specific application. Therefore, a fundamental understanding of the multiscale structure of fibers and its correlation with their macroscopic behaviors is required for the design and production of systems with dedicated applications. In this study, we demonstrate that the properties of poly(vinylidene fluoride-co-hexafluoro propylene) (PVDF-HFP) electrospun fibers can be tuned by changing the rotating drum speed used as a collector during electrospinning. Indeed, with the help of multiscale characterization techniques such as scanning electron microscopy (SEM), small-angle X-ray scattering (SAXS), and wide-angle X-ray scattering (WAXS), we observe that increasing the rotating drum speed not only aligns the fibers but also induces polymeric chain rearrangements at the molecular scale. Such changes result in enhanced mechanical properties and an increase of the piezoelectric β-phase of the PVDF-HFP fiber membranes. We detect nanostructural deformation behaviors when the aligned fibrous membrane is uniaxially stretched along the fiber alignment direction, while an increase in the alignment of the fibers is observed for randomly aligned samples. This was analyzed by performing in situ SAXS measurements coupled with uniaxial tensile loading of the fibrous membranes along the fiber alignment direction. The present study shows that fibrous membranes can be produced with varying degrees of fiber orientation, piezoelectric β-phase content, and mechanical properties by controlling the speed of the rotating drum collector during the fiber production. Such aligned fiber membranes have potential applications for neural or musculoskeletal tissue engineering. RSC 2021-11-15 /pmc/articles/PMC8765355/ /pubmed/35178501 http://dx.doi.org/10.1039/d1na00503k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Maurya, Anjani K.
Mias, Eloïse
Schoeller, Jean
Collings, Ines E.
Rossi, René M.
Dommann, Alex
Neels, Antonia
Understanding multiscale structure–property correlations in PVDF-HFP electrospun fiber membranes by SAXS and WAXS
title Understanding multiscale structure–property correlations in PVDF-HFP electrospun fiber membranes by SAXS and WAXS
title_full Understanding multiscale structure–property correlations in PVDF-HFP electrospun fiber membranes by SAXS and WAXS
title_fullStr Understanding multiscale structure–property correlations in PVDF-HFP electrospun fiber membranes by SAXS and WAXS
title_full_unstemmed Understanding multiscale structure–property correlations in PVDF-HFP electrospun fiber membranes by SAXS and WAXS
title_short Understanding multiscale structure–property correlations in PVDF-HFP electrospun fiber membranes by SAXS and WAXS
title_sort understanding multiscale structure–property correlations in pvdf-hfp electrospun fiber membranes by saxs and waxs
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765355/
https://www.ncbi.nlm.nih.gov/pubmed/35178501
http://dx.doi.org/10.1039/d1na00503k
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