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Cyclohexyl-griselimycin Is Active against Mycobacterium abscessus in Mice

Cyclohexyl-griselimycin is a preclinical candidate for use against tuberculosis (TB). Here, we show that this oral cyclodepsipeptide is also active against the intrinsically drug-resistant nontuberculous mycobacterium Mycobacterium abscessus in vitro and in a mouse model of infection. This adds a no...

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Detalles Bibliográficos
Autores principales:	Aragaw, Wassihun Wedajo, Roubert, Christine, Fontaine, Evelyne, Lagrange, Sophie, Zimmerman, Matthew D., Dartois, Véronique, Gengenbacher, Martin, Dick, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765428/ https://www.ncbi.nlm.nih.gov/pubmed/34723632 http://dx.doi.org/10.1128/AAC.01400-21

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