GSK3640254 Is a Novel HIV-1 Maturation Inhibitor with an Optimized Virology Profile

HIV-1 maturation inhibitors (MIs) offer a novel mechanism of action and potential for use in HIV-1 treatment. Prior MIs displayed clinical efficacy but were associated with the emergence of resistance and some gastrointestinal tolerability events. Treatment with the potentially safer next-generation...

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Detalles Bibliográficos
Autores principales: Dicker, Ira, Jeffrey, Jerry L., Protack, Tricia, Lin, Zeyu, Cockett, Mark, Chen, Yan, Sit, Sing-Yuen, Gartland, Martin, Meanwell, Nicholas A., Regueiro-Ren, Alicia, Drexler, Dieter, Cantone, Joseph, McAuliffe, Brian, Krystal, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765437/
https://www.ncbi.nlm.nih.gov/pubmed/34780263
http://dx.doi.org/10.1128/AAC.01876-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765437/
https://www.ncbi.nlm.nih.gov/pubmed/34780263
http://dx.doi.org/10.1128/AAC.01876-21

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