How is insulin-like growth factor-1 correlated with retinopathy of prematurity?

BACKGROUND: Evaluation of insulin-like growth factor-1 (IGF-1) association with retinopathy of prematurity (ROP) is our object. MATERIALS AND METHODS: This study was conducted on IGF-1 levels of 40 neonates <34 weeks gestational age and 2000 g at 1(st) week and 4–6 weeks after birth. All particip...

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Detalles Bibliográficos
Autores principales: Jafari, Nahid, Karimi Moghadam, Arezoo, Taslimi Taleghani, Naeeme, Hosseini Nezhad, Neda, Motamed, Nima, Jalilvand, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765505/
https://www.ncbi.nlm.nih.gov/pubmed/35126574
http://dx.doi.org/10.4103/jrms.JRMS_501_20
Descripción
Sumario:BACKGROUND: Evaluation of insulin-like growth factor-1 (IGF-1) association with retinopathy of prematurity (ROP) is our object. MATERIALS AND METHODS: This study was conducted on IGF-1 levels of 40 neonates <34 weeks gestational age and 2000 g at 1(st) week and 4–6 weeks after birth. All participants were evaluated for ROP after 31 weeks of gestation. RESULTS: IGF-1 levels showed a significant difference between neonates ≤1500 and 1500–2000 g (1 and 4–6 weeks, P = 0.008, P = 0.039, respectively). No significant association was found between IGF-1 and ROP. CONCLUSION: Finding a meaningful association between IGF-1 and ROP requires consideration of factors affecting the IGF-1.

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