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Iron-Dependent Mitochondrial Dysfunction Contributes to the Pathogenesis of Pulmonary Fibrosis

Although the pathogenesis of pulmonary fibrosis remains unclear, it is known to involve epithelial injury and epithelial-mesenchymal transformation (EMT) as a consequence of cigarette smoke (CS) exposure. Moreover, smoking deposits iron in the mitochondria of alveolar epithelial cells. Iron overload...

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Detalles Bibliográficos
Autores principales:	Takahashi, Mai, Mizumura, Kenji, Gon, Yasuhiro, Shimizu, Tetsuo, Kozu, Yutaka, Shikano, Sotaro, Iida, Yuko, Hikichi, Mari, Okamoto, Shinichi, Tsuya, Kota, Fukuda, Asami, Yamada, Shiho, Soda, Kaori, Hashimoto, Shu, Maruoka, Shuichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765595/ https://www.ncbi.nlm.nih.gov/pubmed/35058772 http://dx.doi.org/10.3389/fphar.2021.643980

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