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Preformation and epigenesis converge to specify primordial germ cell fate in the early Drosophila embryo
A critical step in animal development is the specification of primordial germ cells (PGCs), the precursors of the germline. Two seemingly mutually exclusive mechanisms are implemented across the animal kingdom: epigenesis and preformation. In epigenesis, PGC specification is non-autonomous and depen...
Autores principales: | Colonnetta, Megan M., Goyal, Yogesh, Johnson, Heath E., Syal, Sapna, Schedl, Paul, Deshpande, Girish |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765614/ https://www.ncbi.nlm.nih.gov/pubmed/34986144 http://dx.doi.org/10.1371/journal.pgen.1010002 |
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