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Effect of prorenin peptide vaccine on the early phase of diabetic retinopathy in a murine model of type 2 diabetes
Prorenin is viewed as an ideal target molecule in the prevention of diabetic retinopathy. However, no drugs are available for inhibiting activation of prorenin. Here, we tested the effect of a prorenin peptide vaccine (V(P)) in the retina of a murine model of type 2 diabetes (T2D). To choose the opt...
Autores principales: | Yokota, Harumasa, Hayashi, Hiroki, Hanaguri, Junya, Yamagami, Satoru, Kushiyama, Akifumi, Nakagami, Hironori, Nagaoka, Taiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765632/ https://www.ncbi.nlm.nih.gov/pubmed/35041699 http://dx.doi.org/10.1371/journal.pone.0262568 |
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