DAJIN enables multiplex genotyping to simultaneously validate intended and unintended target genome editing outcomes

Genome editing can introduce designed mutations into a target genomic site. Recent research has revealed that it can also induce various unintended events such as structural variations, small indels, and substitutions at, and in some cases, away from the target site. These rearrangements may result...

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Detalles Bibliográficos
Autores principales: Kuno, Akihiro, Ikeda, Yoshihisa, Ayabe, Shinya, Kato, Kanako, Sakamoto, Kotaro, Suzuki, Sayaka R., Morimoto, Kento, Wakimoto, Arata, Mikami, Natsuki, Ishida, Miyuki, Iki, Natsumi, Hamada, Yuko, Takemura, Megumi, Daitoku, Yoko, Tanimoto, Yoko, Dinh, Tra Thi Huong, Murata, Kazuya, Hamada, Michito, Muratani, Masafumi, Yoshiki, Atsushi, Sugiyama, Fumihiro, Takahashi, Satoru, Mizuno, Seiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765641/
https://www.ncbi.nlm.nih.gov/pubmed/35041655
http://dx.doi.org/10.1371/journal.pbio.3001507

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