Promotor Hypomethylation Mediated Upregulation of miR-23b-3p Targets PTEN to Promote Bronchial Epithelial-Mesenchymal Transition in Chronic Asthma

Chronic asthma is characterized by airway inflammation and irreversible airway remodeling. Epithelial-mesenchymal transition (EMT) is a typical pathological change of airway remodeling. Our previous research demonstrated miR-23b inhibited airway smooth muscle proliferation while the function of miR-...

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Detalles Bibliográficos
Autores principales: Guo, Yimin, Yuan, Xiaoqing, Hong, Luna, Wang, Qiujie, Liu, Shanying, Li, Zhaolin, Huang, Linjie, Jiang, Shanping, Shi, Jianting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765721/
https://www.ncbi.nlm.nih.gov/pubmed/35058921
http://dx.doi.org/10.3389/fimmu.2021.771216

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