Simvastatin Improves Myocardial Ischemia Reperfusion Injury through KLF-Regulated Alleviation of Inflammation

OBJECTIVE: To clarify the protective effect of simvastatin on myocardial ischemia reperfusion injury (MIRI) and the underlying mechanism. MATERIALS AND METHODS: The MIRI model in rats was firstly constructed. Twenty-four male rats were randomly assigned into the sham group, ischemia-reperfusion (I/R...

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Detalles Bibliográficos
Autores principales: Wei, Tingju, Li, Jun, Fu, Guowei, Zhao, Hui, Huang, Chen, Zhu, Xiaohua, Huang, Gongcheng, Xu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766176/
https://www.ncbi.nlm.nih.gov/pubmed/35059045
http://dx.doi.org/10.1155/2022/7878602

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