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Aortic valve neocuspidization for aortic regurgitation associated with ventricular septal defect

 : OBJECTIVES: Different methods of aortic valve repair have been described in the literature for aortic regurgitation (AR) associated with doubly committed subarterial ventricular septal defects. Our goal was to present our experience with aortic valve reconstruction of a single leaflet using the a...

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Autores principales: Sivalingam, Sivakumar, Haranal, Maruti, Pathan, Iqbal Hussain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766201/
https://www.ncbi.nlm.nih.gov/pubmed/34499736
http://dx.doi.org/10.1093/icvts/ivab239
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author Sivalingam, Sivakumar
Haranal, Maruti
Pathan, Iqbal Hussain
author_facet Sivalingam, Sivakumar
Haranal, Maruti
Pathan, Iqbal Hussain
author_sort Sivalingam, Sivakumar
collection PubMed
description  : OBJECTIVES: Different methods of aortic valve repair have been described in the literature for aortic regurgitation (AR) associated with doubly committed subarterial ventricular septal defects. Our goal was to present our experience with aortic valve reconstruction of a single leaflet using the aortic valve neocuspidization technique in this subset of patients. METHODS: It is a retrospective review of 7 patients with doubly committed subarterial ventricular septal defects with significant (>moderate) AR who underwent the single-leaflet neocuspidization technique of aortic valve reconstruction from January 2016 to January 2019. Data were collected from medical records. All patients had thorough 2-dimensional echocardiographic assessment preoperatively and during the follow-up period. Primary end points were freedom from postoperative AR and freedom from reoperation and all-cause mortality within the follow-up period with secondary end points of freedom from thromboembolism and infective endocarditis. RESULTS: Out of 7 patients, 6 were male and 1 was female. There were no perioperative deaths. The mean follow-up period was 2.6 ± 0.8 years. No deaths occurred during the follow-up period. At the latest follow-up examination, only 2 patients showed mild AR and were asymptomatic. There was no documented event of infective endocarditis or thromboembolism during the follow-up period. CONCLUSIONS: The aortic leaflet neocuspidization procedure for the aortic valve is a relatively new concept. Availability of a template makes it an easily reproducible valve repair in paediatric patients with a single-leaflet abnormality. This technique preserves the remaining 2 normal leaflets, thus promoting the growth potential while maintaining near normal aortic root complex dynamics.
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spelling pubmed-87662012022-01-19 Aortic valve neocuspidization for aortic regurgitation associated with ventricular septal defect Sivalingam, Sivakumar Haranal, Maruti Pathan, Iqbal Hussain Interact Cardiovasc Thorac Surg Congenital  : OBJECTIVES: Different methods of aortic valve repair have been described in the literature for aortic regurgitation (AR) associated with doubly committed subarterial ventricular septal defects. Our goal was to present our experience with aortic valve reconstruction of a single leaflet using the aortic valve neocuspidization technique in this subset of patients. METHODS: It is a retrospective review of 7 patients with doubly committed subarterial ventricular septal defects with significant (>moderate) AR who underwent the single-leaflet neocuspidization technique of aortic valve reconstruction from January 2016 to January 2019. Data were collected from medical records. All patients had thorough 2-dimensional echocardiographic assessment preoperatively and during the follow-up period. Primary end points were freedom from postoperative AR and freedom from reoperation and all-cause mortality within the follow-up period with secondary end points of freedom from thromboembolism and infective endocarditis. RESULTS: Out of 7 patients, 6 were male and 1 was female. There were no perioperative deaths. The mean follow-up period was 2.6 ± 0.8 years. No deaths occurred during the follow-up period. At the latest follow-up examination, only 2 patients showed mild AR and were asymptomatic. There was no documented event of infective endocarditis or thromboembolism during the follow-up period. CONCLUSIONS: The aortic leaflet neocuspidization procedure for the aortic valve is a relatively new concept. Availability of a template makes it an easily reproducible valve repair in paediatric patients with a single-leaflet abnormality. This technique preserves the remaining 2 normal leaflets, thus promoting the growth potential while maintaining near normal aortic root complex dynamics. Oxford University Press 2021-09-09 /pmc/articles/PMC8766201/ /pubmed/34499736 http://dx.doi.org/10.1093/icvts/ivab239 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Congenital
Sivalingam, Sivakumar
Haranal, Maruti
Pathan, Iqbal Hussain
Aortic valve neocuspidization for aortic regurgitation associated with ventricular septal defect
title Aortic valve neocuspidization for aortic regurgitation associated with ventricular septal defect
title_full Aortic valve neocuspidization for aortic regurgitation associated with ventricular septal defect
title_fullStr Aortic valve neocuspidization for aortic regurgitation associated with ventricular septal defect
title_full_unstemmed Aortic valve neocuspidization for aortic regurgitation associated with ventricular septal defect
title_short Aortic valve neocuspidization for aortic regurgitation associated with ventricular septal defect
title_sort aortic valve neocuspidization for aortic regurgitation associated with ventricular septal defect
topic Congenital
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766201/
https://www.ncbi.nlm.nih.gov/pubmed/34499736
http://dx.doi.org/10.1093/icvts/ivab239
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