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Detection of occludable angle with anterior segment optical coherence tomography and Pentacam as non-contact screening methods
PURPOSE: To evaluate diagnostic capacity for occludable anterior chamber angle detection with anterior segment optical coherence tomography (AS-OCT) and Pentacam. METHODS: Observational cross-sectional study with AS-OCT and Pentacam. AS-OCT measures: angle opening distance from Schwalbe line (SL) pe...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766219/ https://www.ncbi.nlm.nih.gov/pubmed/35043245 http://dx.doi.org/10.1007/s10792-021-02208-y |
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author | Benitez-del-Castillo, Javier Nowrouzi, Ali Rodriguez-Calzadilla, Mario Mota-Chozas, Inmaculada Pinazo-Duran, Maria Dolores |
author_facet | Benitez-del-Castillo, Javier Nowrouzi, Ali Rodriguez-Calzadilla, Mario Mota-Chozas, Inmaculada Pinazo-Duran, Maria Dolores |
author_sort | Benitez-del-Castillo, Javier |
collection | PubMed |
description | PURPOSE: To evaluate diagnostic capacity for occludable anterior chamber angle detection with anterior segment optical coherence tomography (AS-OCT) and Pentacam. METHODS: Observational cross-sectional study with AS-OCT and Pentacam. AS-OCT measures: angle opening distance from Schwalbe line (SL) perpendicular (AOD-SL-Perp) and vertical to iris (AOD-SL-Vert), and iridotrabecular angle (ITA). Pentacam measures: anterior chamber depth (ACD), anterior chamber volume (ACV), and anterior chamber angle (ACA). We analysed Spearman’s correlation with gonioscopic classification. Area under receiver operating characteristic curves (AUCs) for occludable angle detection were compared. Agreement between iridocorneal values of methods was evaluated. RESULTS: Seventy-four left eyes of 74 patients. Correlation between temporal AS-OCT and gonioscopy: 0.83 (p < 0.0001) AOD-SL-Perp temporal, 0.82 (p < 0.0001) AOD-SL-Vert temporal, and 0.69 (p < 0.0001) ITA temporal. Correlation between AS-OCT nasal and gonioscopy: 0.74 (p < 0.0001) AOD-SL-Perp nasal, 0.74 (p < 0.0001) AOD-SL-Vert nasal, and 0.70 (p < 0.0001) ITA nasal. Correlation of Pentacam with temporal gonioscopy: 0.57 (p < 0.0001) ACD, 0.56 (p < 0.0001) ACV, and 0.63 (p < 0.0001) ACA. Correlation of Pentacam with nasal gonioscopy: 0.47 (IC 0.27–0.73, p < 0.0001) ACD, 0.49 (p < 0.0001) ACV, and 0.56 (CI 0.38–0.7, p < 0.0001) ACA. AS-OCT AUCs: AOD-SL-Perp temporal 0.89 (CI 0.80–0.95), AOD-SL-Vert 0.87 (CI 0.77–0.94), ITA temporal 0.88 (CI 0.78–0.94), AOD-SL-Perp nasal 0.83 (CI 0.72–0.91), AOD-SL-Vert nasal 0.87 (CI 0.77–0.94), and ITA nasal 0.91 (IC 0.81–0.96). Pentacam AUCs: ACD 0.76 (CI 0.64–0.85), ACV 0.75 (CI 0.63–0.84), and ACA 0.84 (CI 0.74–0.92). No statistical differences between different AUCs. Intraclass correlation coefficient (ICC) of ACA (Pentacam) with ITA temporal (AS-OCT) 0.59 and with nasal ITA nasal (AS-OCT) 0.65. CONCLUSION: Both systems show high capacity for non-contact occludable angle detection. But agreement between methods is moderate or low. |
format | Online Article Text |
id | pubmed-8766219 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-87662192022-01-19 Detection of occludable angle with anterior segment optical coherence tomography and Pentacam as non-contact screening methods Benitez-del-Castillo, Javier Nowrouzi, Ali Rodriguez-Calzadilla, Mario Mota-Chozas, Inmaculada Pinazo-Duran, Maria Dolores Int Ophthalmol Original Paper PURPOSE: To evaluate diagnostic capacity for occludable anterior chamber angle detection with anterior segment optical coherence tomography (AS-OCT) and Pentacam. METHODS: Observational cross-sectional study with AS-OCT and Pentacam. AS-OCT measures: angle opening distance from Schwalbe line (SL) perpendicular (AOD-SL-Perp) and vertical to iris (AOD-SL-Vert), and iridotrabecular angle (ITA). Pentacam measures: anterior chamber depth (ACD), anterior chamber volume (ACV), and anterior chamber angle (ACA). We analysed Spearman’s correlation with gonioscopic classification. Area under receiver operating characteristic curves (AUCs) for occludable angle detection were compared. Agreement between iridocorneal values of methods was evaluated. RESULTS: Seventy-four left eyes of 74 patients. Correlation between temporal AS-OCT and gonioscopy: 0.83 (p < 0.0001) AOD-SL-Perp temporal, 0.82 (p < 0.0001) AOD-SL-Vert temporal, and 0.69 (p < 0.0001) ITA temporal. Correlation between AS-OCT nasal and gonioscopy: 0.74 (p < 0.0001) AOD-SL-Perp nasal, 0.74 (p < 0.0001) AOD-SL-Vert nasal, and 0.70 (p < 0.0001) ITA nasal. Correlation of Pentacam with temporal gonioscopy: 0.57 (p < 0.0001) ACD, 0.56 (p < 0.0001) ACV, and 0.63 (p < 0.0001) ACA. Correlation of Pentacam with nasal gonioscopy: 0.47 (IC 0.27–0.73, p < 0.0001) ACD, 0.49 (p < 0.0001) ACV, and 0.56 (CI 0.38–0.7, p < 0.0001) ACA. AS-OCT AUCs: AOD-SL-Perp temporal 0.89 (CI 0.80–0.95), AOD-SL-Vert 0.87 (CI 0.77–0.94), ITA temporal 0.88 (CI 0.78–0.94), AOD-SL-Perp nasal 0.83 (CI 0.72–0.91), AOD-SL-Vert nasal 0.87 (CI 0.77–0.94), and ITA nasal 0.91 (IC 0.81–0.96). Pentacam AUCs: ACD 0.76 (CI 0.64–0.85), ACV 0.75 (CI 0.63–0.84), and ACA 0.84 (CI 0.74–0.92). No statistical differences between different AUCs. Intraclass correlation coefficient (ICC) of ACA (Pentacam) with ITA temporal (AS-OCT) 0.59 and with nasal ITA nasal (AS-OCT) 0.65. CONCLUSION: Both systems show high capacity for non-contact occludable angle detection. But agreement between methods is moderate or low. Springer Netherlands 2022-01-19 2022 /pmc/articles/PMC8766219/ /pubmed/35043245 http://dx.doi.org/10.1007/s10792-021-02208-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Paper Benitez-del-Castillo, Javier Nowrouzi, Ali Rodriguez-Calzadilla, Mario Mota-Chozas, Inmaculada Pinazo-Duran, Maria Dolores Detection of occludable angle with anterior segment optical coherence tomography and Pentacam as non-contact screening methods |
title | Detection of occludable angle with anterior segment optical coherence tomography and Pentacam as non-contact screening methods |
title_full | Detection of occludable angle with anterior segment optical coherence tomography and Pentacam as non-contact screening methods |
title_fullStr | Detection of occludable angle with anterior segment optical coherence tomography and Pentacam as non-contact screening methods |
title_full_unstemmed | Detection of occludable angle with anterior segment optical coherence tomography and Pentacam as non-contact screening methods |
title_short | Detection of occludable angle with anterior segment optical coherence tomography and Pentacam as non-contact screening methods |
title_sort | detection of occludable angle with anterior segment optical coherence tomography and pentacam as non-contact screening methods |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766219/ https://www.ncbi.nlm.nih.gov/pubmed/35043245 http://dx.doi.org/10.1007/s10792-021-02208-y |
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