Natural Killer Cells Are Present in Rag1(−/−) Mice and Promote Tissue Damage During the Acute Phase of Ischemic Stroke

Rag1(−/−) mice, lacking functional B and T cells, have been extensively used as an adoptive transfer model to evaluate neuroinflammation in stroke research. However, it remains unknown whether natural killer (NK) cell development and functions are altered in Rag1(−/−) mice as well. This connection h...

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Detalles Bibliográficos
Autores principales: Rolfes, Leoni, Ruck, Tobias, David, Christina, Mencl, Stine, Bock, Stefanie, Schmidt, Mariella, Strecker, Jan-Kolja, Pfeuffer, Steffen, Mecklenbeck, Andreas-Schulte, Gross, Catharina, Gliem, Michael, Minnerup, Jens, Schuhmann, Michael K., Kleinschnitz, Christoph, Meuth, Sven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766401/
https://www.ncbi.nlm.nih.gov/pubmed/34105078
http://dx.doi.org/10.1007/s12975-021-00923-3

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