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Inhibiting TLR7 Expression in the Retinal Pigment Epithelium Suppresses Experimental Autoimmune Uveitis

Experimental autoimmune uveitis (EAU), a model of human uveitis, is an organ-specific, T cell-mediated autoimmune disease. Autoreactive T cells can penetrate the blood-retinal barrier, which is a physical defense composed of tight junction-linked retinal pigment epithelial (RPE) cells. RPE cells ser...

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Detalles Bibliográficos
Autores principales:	Lo, Sheng-Min, Hwang, Yih-Shiou, Liu, Chao-Lin, Shen, Chia-Ning, Hong, Wei-Hsin, Yang, Wei-Cheng, Lee, Meng-Hua, Shen, Chia-Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766412/ https://www.ncbi.nlm.nih.gov/pubmed/35069523 http://dx.doi.org/10.3389/fimmu.2021.736261

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