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Role of Nanotechnology and Their Perspectives in the Treatment of Kidney Diseases

Nanoparticles (NPs) are differing in particle size, charge, shape, and compatibility of targeting ligands, which are linked to improved pharmacologic characteristics, targetability, and bioavailability. Researchers are now tasked with developing a solution for enhanced renal treatment that is free o...

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Detalles Bibliográficos
Autores principales: Merlin, J. P. Jose, Li, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766413/
https://www.ncbi.nlm.nih.gov/pubmed/35069707
http://dx.doi.org/10.3389/fgene.2021.817974
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author Merlin, J. P. Jose
Li, Xiaogang
author_facet Merlin, J. P. Jose
Li, Xiaogang
author_sort Merlin, J. P. Jose
collection PubMed
description Nanoparticles (NPs) are differing in particle size, charge, shape, and compatibility of targeting ligands, which are linked to improved pharmacologic characteristics, targetability, and bioavailability. Researchers are now tasked with developing a solution for enhanced renal treatment that is free of side effects and delivers the medicine to the active spot. A growing number of nano-based medication delivery devices are being used to treat renal disorders. Kidney disease management and treatment are currently causing a substantial global burden. Renal problems are multistep processes involving the accumulation of a wide range of molecular and genetic alterations that have been related to a variety of kidney diseases. Renal filtration is a key channel for drug elimination in the kidney, as well as a burgeoning topic of nanomedicine. Although the use of nanotechnology in the treatment of renal illnesses is still in its early phases, it offers a lot of potentials. In this review, we summarized the properties of the kidney and characteristics of drug delivery systems, which affect a drug’s ability should focus on the kidney and highlight the possibilities, problems, and opportunities.
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spelling pubmed-87664132022-01-20 Role of Nanotechnology and Their Perspectives in the Treatment of Kidney Diseases Merlin, J. P. Jose Li, Xiaogang Front Genet Genetics Nanoparticles (NPs) are differing in particle size, charge, shape, and compatibility of targeting ligands, which are linked to improved pharmacologic characteristics, targetability, and bioavailability. Researchers are now tasked with developing a solution for enhanced renal treatment that is free of side effects and delivers the medicine to the active spot. A growing number of nano-based medication delivery devices are being used to treat renal disorders. Kidney disease management and treatment are currently causing a substantial global burden. Renal problems are multistep processes involving the accumulation of a wide range of molecular and genetic alterations that have been related to a variety of kidney diseases. Renal filtration is a key channel for drug elimination in the kidney, as well as a burgeoning topic of nanomedicine. Although the use of nanotechnology in the treatment of renal illnesses is still in its early phases, it offers a lot of potentials. In this review, we summarized the properties of the kidney and characteristics of drug delivery systems, which affect a drug’s ability should focus on the kidney and highlight the possibilities, problems, and opportunities. Frontiers Media S.A. 2022-01-05 /pmc/articles/PMC8766413/ /pubmed/35069707 http://dx.doi.org/10.3389/fgene.2021.817974 Text en Copyright © 2022 Merlin and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Merlin, J. P. Jose
Li, Xiaogang
Role of Nanotechnology and Their Perspectives in the Treatment of Kidney Diseases
title Role of Nanotechnology and Their Perspectives in the Treatment of Kidney Diseases
title_full Role of Nanotechnology and Their Perspectives in the Treatment of Kidney Diseases
title_fullStr Role of Nanotechnology and Their Perspectives in the Treatment of Kidney Diseases
title_full_unstemmed Role of Nanotechnology and Their Perspectives in the Treatment of Kidney Diseases
title_short Role of Nanotechnology and Their Perspectives in the Treatment of Kidney Diseases
title_sort role of nanotechnology and their perspectives in the treatment of kidney diseases
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766413/
https://www.ncbi.nlm.nih.gov/pubmed/35069707
http://dx.doi.org/10.3389/fgene.2021.817974
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