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Novel regulation mechanism of adrenal cortisol and DHEA biosynthesis via the endogen ERAD inhibitor small VCP-interacting protein

Endoplasmic reticulum-associated degradation (ERAD) is a well-characterized mechanism of protein quality control by removal of misfolded or unfolded proteins. The tight regulation of ERAD is critical for protein homeostasis as well as lipid metabolism. Although the mechanism is complex, all ERAD bra...

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Detalles Bibliográficos
Autores principales: Ilhan, Recep, Üner, Göklem, Yilmaz, Sinem, Atalay Sahar, Esra, Cayli, Sevil, Erzurumlu, Yalcin, Gozen, Oguz, Ballar Kirmizibayrak, Petek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766438/
https://www.ncbi.nlm.nih.gov/pubmed/35042898
http://dx.doi.org/10.1038/s41598-022-04821-y