A 6-mRNA host response classifier in whole blood predicts outcomes in COVID-19 and other acute viral infections

Predicting the severity of COVID-19 remains an unmet medical need. Our objective was to develop a blood-based host-gene-expression classifier for the severity of viral infections and validate it in independent data, including COVID-19. We developed a logistic regression-based classifier for the seve...

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Detalles Bibliográficos
Autores principales: Buturovic, Ljubomir, Zheng, Hong, Tang, Benjamin, Lai, Kevin, Kuan, Win Sen, Gillett, Mark, Santram, Rahul, Shojaei, Maryam, Almansa, Raquel, Nieto, Jose Ángel, Muñoz, Sonsoles, Herrero, Carmen, Antonakos, Nikolaos, Koufargyris, Panayiotis, Kontogiorgi, Marina, Damoraki, Georgia, Liesenfeld, Oliver, Wacker, James, Midic, Uros, Luethy, Roland, Rawling, David, Remmel, Melissa, Coyle, Sabrina, Liu, Yiran E., Rao, Aditya M., Dermadi, Denis, Toh, Jiaying, Jones, Lara Murphy, Donato, Michele, Khatri, Purvesh, Giamarellos-Bourboulis, Evangelos J., Sweeney, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766462/
https://www.ncbi.nlm.nih.gov/pubmed/35042868
http://dx.doi.org/10.1038/s41598-021-04509-9

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