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Ophthalmic complications in retinopathy of prematurity in the first decade of life in Korea using the national health insurance database

The aim of this study is to investigate the epidemiology of ophthalmic complications of retinopathy of prematurity (ROP) after preterm birth using population-based database in South Korea. Using the National Health Insurance database, ophthalmic complications among premature infants born in 2007–200...

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Autores principales: Hong, Eun Hee, Shin, Yong Un, Bae, Gi Hwan, Choi, Young Jin, Ahn, Seong Joon, Kim, Inah, Cho, Heeyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766475/
https://www.ncbi.nlm.nih.gov/pubmed/35042903
http://dx.doi.org/10.1038/s41598-021-04616-7
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author Hong, Eun Hee
Shin, Yong Un
Bae, Gi Hwan
Choi, Young Jin
Ahn, Seong Joon
Kim, Inah
Cho, Heeyoon
author_facet Hong, Eun Hee
Shin, Yong Un
Bae, Gi Hwan
Choi, Young Jin
Ahn, Seong Joon
Kim, Inah
Cho, Heeyoon
author_sort Hong, Eun Hee
collection PubMed
description The aim of this study is to investigate the epidemiology of ophthalmic complications of retinopathy of prematurity (ROP) after preterm birth using population-based database in South Korea. Using the National Health Insurance database, ophthalmic complications among premature infants born in 2007–2008 during their 10-year follow-up period were identified. Annual cumulative incidence rate and period prevalence of complications at each age were analyzed among those with ROP and those who underwent treatment for ROP (tROP). The hazard ratios (HRs) according to the presence of ROP and treatment for ROP were also analyzed. We identified 18,256 premature infants, 6995 of whom had ROP. The prevalence at 10th year for overall ophthalmic complications was 11.1% and 35.9% among ROP and tROP, respectively. Strabismus, amblyopia, and glaucoma were the three most common complications. The presence of ROP was associated with higher risk of complications (HR 1.53, 95%CI 1.44–1.61) among premature infants, and the presence of treatment for ROP was associated with higher risk of complications (HR 4.31, 95%CI 3.74–4.98) among ROP cases. This study reports the nationwide epidemiologic data on ophthalmic complications of ROP during the first decade of life, which will help advance our understandings and establish national strategies in managing ROP.
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spelling pubmed-87664752022-01-20 Ophthalmic complications in retinopathy of prematurity in the first decade of life in Korea using the national health insurance database Hong, Eun Hee Shin, Yong Un Bae, Gi Hwan Choi, Young Jin Ahn, Seong Joon Kim, Inah Cho, Heeyoon Sci Rep Article The aim of this study is to investigate the epidemiology of ophthalmic complications of retinopathy of prematurity (ROP) after preterm birth using population-based database in South Korea. Using the National Health Insurance database, ophthalmic complications among premature infants born in 2007–2008 during their 10-year follow-up period were identified. Annual cumulative incidence rate and period prevalence of complications at each age were analyzed among those with ROP and those who underwent treatment for ROP (tROP). The hazard ratios (HRs) according to the presence of ROP and treatment for ROP were also analyzed. We identified 18,256 premature infants, 6995 of whom had ROP. The prevalence at 10th year for overall ophthalmic complications was 11.1% and 35.9% among ROP and tROP, respectively. Strabismus, amblyopia, and glaucoma were the three most common complications. The presence of ROP was associated with higher risk of complications (HR 1.53, 95%CI 1.44–1.61) among premature infants, and the presence of treatment for ROP was associated with higher risk of complications (HR 4.31, 95%CI 3.74–4.98) among ROP cases. This study reports the nationwide epidemiologic data on ophthalmic complications of ROP during the first decade of life, which will help advance our understandings and establish national strategies in managing ROP. Nature Publishing Group UK 2022-01-18 /pmc/articles/PMC8766475/ /pubmed/35042903 http://dx.doi.org/10.1038/s41598-021-04616-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Hong, Eun Hee
Shin, Yong Un
Bae, Gi Hwan
Choi, Young Jin
Ahn, Seong Joon
Kim, Inah
Cho, Heeyoon
Ophthalmic complications in retinopathy of prematurity in the first decade of life in Korea using the national health insurance database
title Ophthalmic complications in retinopathy of prematurity in the first decade of life in Korea using the national health insurance database
title_full Ophthalmic complications in retinopathy of prematurity in the first decade of life in Korea using the national health insurance database
title_fullStr Ophthalmic complications in retinopathy of prematurity in the first decade of life in Korea using the national health insurance database
title_full_unstemmed Ophthalmic complications in retinopathy of prematurity in the first decade of life in Korea using the national health insurance database
title_short Ophthalmic complications in retinopathy of prematurity in the first decade of life in Korea using the national health insurance database
title_sort ophthalmic complications in retinopathy of prematurity in the first decade of life in korea using the national health insurance database
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766475/
https://www.ncbi.nlm.nih.gov/pubmed/35042903
http://dx.doi.org/10.1038/s41598-021-04616-7
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