Repurposing the Pathogen Box compounds for identification of potent anti-malarials against blood stages of Plasmodium falciparum with PfUCHL3 inhibitory activity

Malaria has endured as a global epidemic since ages and its eradication poses an immense challenge due to the complex life cycle of the causative pathogen and its tolerance to a myriad of therapeutics. PfUCHL3, a member of the ubiquitin C-terminal hydrolase (UCH) family of deubiquitinases (DUBs) is...

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Detalles Bibliográficos
Autores principales: Bharti, Hina, Singal, Aakriti, Saini, Manisha, Cheema, Pradeep Singh, Raza, Mohsin, Kundu, Suman, Nag, Alo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766476/
https://www.ncbi.nlm.nih.gov/pubmed/35042884
http://dx.doi.org/10.1038/s41598-021-04619-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766476/
https://www.ncbi.nlm.nih.gov/pubmed/35042884
http://dx.doi.org/10.1038/s41598-021-04619-4

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