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Asymmetric synthesis of N-bridged [3.3.1] ring systems by phosphonium salt/Lewis acid relay catalysis

Optically pure pseudo-natural products (PNPs), particularly exemplified by azabicyclo[3.3.1]nonane molecules and their analogs provide an attractive platform for structure−activity relationship studies, and also lead new compound discovery in drug development. However, there are currently no example...

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Detalles Bibliográficos
Autores principales: Tan, Jian-Ping, Li, Kehan, Shen, Boming, Zhuang, Cheng, Liu, Zanjiao, Xiao, Kai, Yu, Peiyuan, Yi, Bing, Ren, Xiaoyu, Wang, Tianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766524/
https://www.ncbi.nlm.nih.gov/pubmed/35042870
http://dx.doi.org/10.1038/s41467-022-28001-8

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