Paediatric and neonatal sepsis and inflammation

Sepsis has a huge impact on global mortality and has been declared as a priority by the World Health organisation the WHO.(1) Children have a high incidence of sepsis especially in the neonatal with an estimated 3 million babies affected worldwide and mortality ranges from 11 to 19%.(2) In addition,...

Descripción completa

Detalles Bibliográficos
Autores principales: Molloy, E. J., Bearer, C. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766624/
https://www.ncbi.nlm.nih.gov/pubmed/35046541
http://dx.doi.org/10.1038/s41390-021-01918-4
_version_ 1784634568552218624
author Molloy, E. J.
Bearer, C. F.
author_facet Molloy, E. J.
Bearer, C. F.
author_sort Molloy, E. J.
collection PubMed
description Sepsis has a huge impact on global mortality and has been declared as a priority by the World Health organisation the WHO.(1) Children have a high incidence of sepsis especially in the neonatal with an estimated 3 million babies affected worldwide and mortality ranges from 11 to 19%.(2) In addition, long-term neurodevelopmental outcomes are affected but this is largely unquantified. However, challenges remain in the early recognition, diagnosis and standardised management of sepsis. This series on Sepsis and inflammation in children reviews the conundrums of diagnostic criteria, biomarkers, management and future strategies to improve outcomes.
format Online
Article
Text
id pubmed-8766624
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group US
record_format MEDLINE/PubMed
spelling pubmed-87666242022-01-19 Paediatric and neonatal sepsis and inflammation Molloy, E. J. Bearer, C. F. Pediatr Res Editorial Sepsis has a huge impact on global mortality and has been declared as a priority by the World Health organisation the WHO.(1) Children have a high incidence of sepsis especially in the neonatal with an estimated 3 million babies affected worldwide and mortality ranges from 11 to 19%.(2) In addition, long-term neurodevelopmental outcomes are affected but this is largely unquantified. However, challenges remain in the early recognition, diagnosis and standardised management of sepsis. This series on Sepsis and inflammation in children reviews the conundrums of diagnostic criteria, biomarkers, management and future strategies to improve outcomes. Nature Publishing Group US 2022-01-19 2022 /pmc/articles/PMC8766624/ /pubmed/35046541 http://dx.doi.org/10.1038/s41390-021-01918-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Editorial
Molloy, E. J.
Bearer, C. F.
Paediatric and neonatal sepsis and inflammation
title Paediatric and neonatal sepsis and inflammation
title_full Paediatric and neonatal sepsis and inflammation
title_fullStr Paediatric and neonatal sepsis and inflammation
title_full_unstemmed Paediatric and neonatal sepsis and inflammation
title_short Paediatric and neonatal sepsis and inflammation
title_sort paediatric and neonatal sepsis and inflammation
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766624/
https://www.ncbi.nlm.nih.gov/pubmed/35046541
http://dx.doi.org/10.1038/s41390-021-01918-4
work_keys_str_mv AT molloyej paediatricandneonatalsepsisandinflammation
AT bearercf paediatricandneonatalsepsisandinflammation

Ejemplares similares