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Suppressive effects of the neutrophil elastase inhibitor sivelestat sodium hydrate on interleukin-1β production in lipopolysaccharide-stimulated porcine whole blood

OBJECTIVE: Sivelestat sodium hydrate (Siv) is expected to be an effective therapy for acute respiratory distress syndrome, although its mechanism of action is not understood. In this study, we investigated which myeloid cells-derived cytokines were suppressed by Siv. METHODS: Continuous hemofiltrati...

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Detalles Bibliográficos
Autores principales:	Kurimoto, Yasuyoshi, Shimomura, Yasuyo, Moriyama, Kazuhiro, Nakamura, Tomoyuki, Kuriyama, Naohide, Hara, Yoshitaka, Komura, Hidefumi, Hasegawa, Daisuke, Kawaji, Takahiro, Nishida, Osamu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fujita Medical Society 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766654/ https://www.ncbi.nlm.nih.gov/pubmed/35111515 http://dx.doi.org/10.20407/fmj.2019-002

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