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Biosynthesis of Chiral Amino Alcohols via an Engineered Amine Dehydrogenase in E. coli

Chiral amino alcohols are prevalent synthons in pharmaceuticals and synthetic bioactive compounds. The efficient synthesis of chiral amino alcohols using ammonia as the sole amino donor under mild conditions is highly desired and challenging in organic chemistry and biotechnology. Our previous work...

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Detalles Bibliográficos
Autores principales: Tong, Feifei, Qin, Zongmin, Wang, Hongyue, Jiang, Yingying, Li, Junkuan, Ming, Hui, Qu, Ge, Xiao, Yazhong, Sun, Zhoutong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766677/
https://www.ncbi.nlm.nih.gov/pubmed/35071200
http://dx.doi.org/10.3389/fbioe.2021.778584