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Biosynthesis of Chiral Amino Alcohols via an Engineered Amine Dehydrogenase in E. coli
Chiral amino alcohols are prevalent synthons in pharmaceuticals and synthetic bioactive compounds. The efficient synthesis of chiral amino alcohols using ammonia as the sole amino donor under mild conditions is highly desired and challenging in organic chemistry and biotechnology. Our previous work...
Autores principales: | Tong, Feifei, Qin, Zongmin, Wang, Hongyue, Jiang, Yingying, Li, Junkuan, Ming, Hui, Qu, Ge, Xiao, Yazhong, Sun, Zhoutong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766677/ https://www.ncbi.nlm.nih.gov/pubmed/35071200 http://dx.doi.org/10.3389/fbioe.2021.778584 |
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