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Development and Verification of a Hypoxic Gene Signature for Predicting Prognosis, Immune Microenvironment, and Chemosensitivity for Osteosarcoma

Objective: Hypoxic tumors contribute to local failure and distant metastases. Nevertheless, the molecular hallmarks of hypoxia remain ill-defined in osteosarcoma. Here, we developed a hypoxic gene signature in osteosarcoma prognoses. Methods: With the random survival forest algorithm, a prognostic h...

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Detalles Bibliográficos
Autores principales:	Wu, Fengfeng, Xu, Juntao, Jin, Mingchao, Jiang, Xuesheng, Li, Jianyou, Li, Xiongfeng, Chen, Zhuo, Nie, Jiangbo, Meng, Zhipeng, Wang, Guorong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766725/ https://www.ncbi.nlm.nih.gov/pubmed/35071320 http://dx.doi.org/10.3389/fmolb.2021.705148

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