Cargando…
PP2A and Its Inhibitors in Helper T-Cell Differentiation and Autoimmunity
Protein phosphatase 2A (PP2A) is a highly complex heterotrimeric Ser/Thr phosphatase that regulates many cellular processes. The role of PP2A as a tumor suppressor has been extensively studied and reviewed. However, emerging evidence suggests PP2A constrains inflammatory responses and is important i...
Autores principales: | Khan, Mohd Moin, Kalim, Ubaid Ullah, Khan, Meraj H., Lahesmaa, Riitta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766794/ https://www.ncbi.nlm.nih.gov/pubmed/35069561 http://dx.doi.org/10.3389/fimmu.2021.786857 |
Ejemplares similares
-
Long Intergenic Noncoding RNA MIAT as a Regulator of Human Th17 Cell Differentiation
por: Khan, Mohd Moin, et al.
Publicado: (2022) -
Protein interactome of the Cancerous Inhibitor of protein phosphatase 2A (CIP2A) in Th17 cells
por: Khan, Mohd Moin, et al.
Publicado: (2020) -
CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling
por: Khan, Mohd Moin, et al.
Publicado: (2020) -
Gene Set Enrichment Analysis Identifies LIF as a Negative Regulator of Human Th2 Cell Differentiation
por: Ullah, Ubaid, et al.
Publicado: (2012) -
Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation
por: Henriksson, Johan, et al.
Publicado: (2019)