Cargando…

A Novel Tigecycline Adjuvant ML-7 Reverses the Susceptibility of Tigecycline-Resistant Klebsiella pneumoniae

The increasing incidence of tigecycline resistance undoubtedly constitutes a serious threat to global public health. The combination therapies had become the indispensable strategy against this threat. Herein, 11 clinical tigecycline-resistant Klebsiella pneumoniae which mainly has mutations in ramR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Lilan, Sun, Lang, Li, Xue, Hu, Xinxin, Wang, Xiukun, Nie, Tongying, Zhang, Youwen, You, Xuefu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766836/ https://www.ncbi.nlm.nih.gov/pubmed/35071055 http://dx.doi.org/10.3389/fcimb.2021.809542

Ejemplares similares

The Attenuated Protective Effect of Outer Membrane Vesicles Produced by a mcr-1 Positive Strain on Colistin Sensitive Escherichia coli
por: Li, Xue, et al.
Publicado: (2021)

Emergence of Ceftazidime/Avibactam and Tigecycline Resistance in Carbapenem-Resistant Klebsiella pneumoniae Due to In-Host Microevolution
por: Han, Xinhong, et al.
Publicado: (2021)

Proteomics Study of the Synergistic Killing of Tigecycline in Combination With Aminoglycosides Against Carbapenem-Resistant Klebsiella pneumoniae
por: Ma, Xinqian, et al.
Publicado: (2022)

Resistance mechanisms of tigecycline in Acinetobacter baumannii
por: Sun, Chunli, et al.
Publicado: (2023)

Tigecycline Susceptibility and the Role of Efflux Pumps in Tigecycline Resistance in KPC-Producing Klebsiella pneumoniae
por: He, Fang, et al.
Publicado: (2015)

Clinical and microbiological characteristics of tigecycline non-susceptible Klebsiella pneumoniae bacteremia in Taiwan
por: Lin, Yi-Tsung, et al.
Publicado: (2014)

Convergence of MCR-8.2 and Chromosome-Mediated Resistance to Colistin and Tigecycline in an NDM-5-Producing ST656 Klebsiella pneumoniae Isolate From a Lung Transplant Patient in China
por: Zhao, Jiankang, et al.
Publicado: (2022)

Characterization of Tigecycline Resistance Among Tigecycline Non-susceptible Klebsiella pneumoniae Isolates From Humans, Food-Producing Animals, and in vitro Selection Assay
por: Moghimi, Mohaddeseh, et al.
Publicado: (2021)

Evolution of tigecycline resistance in Klebsiella pneumoniae in a single patient
por: Al-Qadheeb, Nada S., et al.
Publicado: (2010)

Emergence of high-level colistin resistance mediated by multiple determinants, including mcr-1.1, mcr-8.2 and crrB mutations, combined with tigecycline resistance in an ST656 Klebsiella pneumoniae
por: Wang, Yanfei, et al.
Publicado: (2023)

Strategies for Rapid Identification of Acinetobacter baumannii Membrane Proteins and Polymyxin B’s Effects
por: Lu, Yun, et al.
Publicado: (2021)

Molecular epidemiology and mechanisms of tigecycline resistance in carbapenem‐resistant Klebsiella pneumoniae isolates
por: Park, Yumi, et al.
Publicado: (2020)

ML364 exerts the broad-spectrum antivirulence effect by interfering with the bacterial quorum sensing system
por: Zhang, Youwen, et al.
Publicado: (2022)

The Resistance Mechanism and Clonal Distribution of Tigecycline-Nonsusceptible Klebsiella pneumoniae Isolates in Korea
por: Ahn, Chulsoo, et al.
Publicado: (2016)

Extended-spectrum β-lactamase Klebsiella pneumoniae meningitis treated with tigecycline
por: Wadi, Jamal Ahmad, et al.
Publicado: (2009)

Tigecycline Resistant Klebsiella pneumoniae Isolated from Austrian River Water
por: Hladicz, Alexander, et al.
Publicado: (2017)

Polymyxin resistance caused by large-scale genomic inversion due to IS26 intramolecular translocation in Klebsiella pneumoniae
por: Li, Haibin, et al.
Publicado: (2023)

Emergence of Colistin Resistance in Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae Under the Pressure of Tigecycline
por: Zhang, Yawei, et al.
Publicado: (2021)

Acquisition of Tigecycline Resistance by Carbapenem-Resistant Klebsiella pneumoniae Confers Collateral Hypersensitivity to Aminoglycosides
por: Chen, Hua-le, et al.
Publicado: (2021)

Presence of Mobile Tigecycline Resistance Gene tet(X4) in Clinical Klebsiella pneumoniae
por: Zhai, Weishuai, et al.
Publicado: (2022)

The Rapid Emergence of Tigecycline Resistance in bla(KPC–2) Harboring Klebsiella pneumoniae, as Mediated in Vivo by Mutation in tetA During Tigecycline Treatment
por: Du, Xiaoxing, et al.
Publicado: (2018)

Safety and effectiveness of tigecycline combination therapy in renal transplant patients with infection due to carbapenem-resistant gram-negative bacteria
por: Wang, Qin, et al.
Publicado: (2023)

Rapid Detection of High-Level Tigecycline Resistance in Tet(X)-Producing Escherichia coli and Acinetobacter spp. Based on MALDI-TOF MS
por: Cui, Ze-Hua, et al.
Publicado: (2020)

In vitro Activity of Pentamidine Alone and in Combination With Aminoglycosides, Tigecycline, Rifampicin, and Doripenem Against Clinical Strains of Carbapenemase-Producing and/or Colistin-Resistant Enterobacteriaceae
por: Cebrero-Cangueiro, Tania, et al.
Publicado: (2018)

Efflux Pump AcrAB Confers Decreased Susceptibility to Piperacillin–Tazobactam and Ceftolozane–Tazobactam in Tigecycline-Non-Susceptible Klebsiella pneumoniae
por: Li, Junjie, et al.
Publicado: (2020)

Combined effect of Polymyxin B and Tigecycline to overcome Heteroresistance in Carbapenem-Resistant Klebsiella pneumoniae
por: Tian, Yuan, et al.
Publicado: (2021)

First Emergence of acrAB and oqxAB Mediated Tigecycline Resistance in Clinical Isolates of Klebsiella pneumoniae Pre-Dating the Use of Tigecycline in a Chinese Hospital
por: Zhong, Xue, et al.
Publicado: (2014)

Impact of Tigecycline’s MIC in the Outcome of Critically Ill Patients with Carbapenemase-Producing Klebsiella pneumoniae Bacteraemia Treated with Tigecycline Monotherapy—Validation of 2019′s EUCAST Proposed Breakpoint Changes
por: Papadimitriou-Olivgeris, Matthaios, et al.
Publicado: (2020)

Efficacy of tigecycline, polymyxin, gentamicin, meropenem and associations in experimental Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae non-lethal sepsis
por: Toledo, Paula Virginia Michelon, et al.
Publicado: (2014)

Change of Hypermucoviscosity in the Development of Tigecycline Resistance in Hypervirulent Klebsiella pneumoniae Sequence Type 23 Strains
por: Park, Suyeon, et al.
Publicado: (2020)

Genomic characterization of tigecycline-resistant Escherichia coli and Klebsiella pneumoniae isolates from hospital sewage
por: Li, Ying, et al.
Publicado: (2023)

Successful High-Dosage Monotherapy of Tigecycline in a Multidrug-Resistant Klebsiella pneumoniae Pneumonia–Septicemia Model in Rats
por: Van der Weide, Hessel, et al.
Publicado: (2020)

Rational use of tigecycline and tigecycline blood concentration monitoring in patients with severe infection
por: Yu, Meiling, et al.
Publicado: (2023)

Fitness of Escherichia coli mutants with reduced susceptibility to tigecycline
por: Linkevicius, Marius, et al.
Publicado: (2016)

Tigecycline-Amikacin Combination Effectively Suppresses the Selection of Resistance in Clinical Isolates of KPC-Producing Klebsiella pneumoniae
por: Ni, Wentao, et al.
Publicado: (2016)

Carbapenemase-producing Klebsiella pneumoniae intra-abdominal infection successfully treated with ceftazidime/avibactam plus tigecycline
por: Guedes, Mariana, et al.
Publicado: (2020)

CusS-CusR Two-Component System Mediates Tigecycline Resistance in Carbapenem-Resistant Klebsiella pneumoniae
por: Chen, Dongjie, et al.
Publicado: (2020)

In vivo Emergence of Colistin and Tigecycline Resistance in Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae During Antibiotics Treatment
por: Chen, Jiawei, et al.
Publicado: (2021)

Resistance evolution of hypervirulent carbapenem-resistant Klebsiella pneumoniae ST11 during treatment with tigecycline and polymyxin
por: Jin, Xi, et al.
Publicado: (2021)

Intrathecal or Intraventricular Tigecycline Therapy for Central Nervous System Infection Associated with Carbapenem-Resistant Klebsiella pneumoniae
por: Du, Ning, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_eqelo706f037frn990ti7grn4g