Cargando…

The Structural Basis of Babesia orientalis Lactate Dehydrogenase

Glycolytic enzymes play a crucial role in the anaerobic glycolysis of apicomplexan parasites for energy generation. Consequently, they are considered as potential targets for new drug development. Previous studies revealed that lactate dehydrogenase (LDH), a glycolytic enzyme, is a potential drug ta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Long, Liu, Qin, Luo, Wanxin, Zhao, Junlong, Alzan, Heba F., He, Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766848/ https://www.ncbi.nlm.nih.gov/pubmed/35071043 http://dx.doi.org/10.3389/fcimb.2021.790101

Ejemplares similares

Lactate Dehydrogenase as a Potential Therapeutic Drug Target to Control Babesia bigemina
por: He, Lan, et al.
Publicado: (2022)

Editorial: Exploring new technologies, investigating new targets, and shedding new light on Babesia
por: Gong, Haiyan, et al.
Publicado: (2022)

Establishment of a Transient and Stable Transfection System for Babesia duncani Using a Homologous Recombination Strategy
por: Wang, Sen, et al.
Publicado: (2022)

Experimental infection of non-immunosuppressed and immunosuppressed goats reveals differential pathogenesis of Babesia aktasi n. sp.
por: Ozubek, Sezayi, et al.
Publicado: (2023)

Characterization of a novel secretory spherical body protein in Babesia orientalis and Babesia orientalis-infected erythrocytes
por: Guo, Jiaying, et al.
Publicado: (2018)

A Historical Overview of Research on Babesia orientalis, a Protozoan Parasite Infecting Water Buffalo
por: He, Lan, et al.
Publicado: (2017)

A Culture-Adapted Strain of Babesia bovis Has Reduced Subpopulation Complexity and Is Unable to Complete Its Natural Life Cycle in Ticks
por: Alzan, Heba F., et al.
Publicado: (2022)

Characterization and annotation of Babesia orientalis apicoplast genome
por: Huang, Yuan, et al.
Publicado: (2015)

Identification of a novel variant erythrocyte surface antigen-1 (VESA1) in Babesia orientalis
por: Han, Zhen, et al.
Publicado: (2021)

Detection of Honeybee Viruses in Vespa orientalis
por: Power, Karen, et al.
Publicado: (2022)

Bacterial Interference With Lactate Dehydrogenase Assay Leads to an Underestimation of Cytotoxicity
por: Van den Bossche, Sara, et al.
Publicado: (2020)

Molecular characterization and genetic diversity of Babesia bovis and Babesia bigemina of cattle in Thailand
por: Srionrod, Nitipon, et al.
Publicado: (2022)

Detection of honey bee viruses in larvae of Vespa orientalis
por: Power, Karen, et al.
Publicado: (2023)

Identification and characterization of extracellular vesicles from red cells infected with Babesia divergens and Babesia microti
por: Beri, Divya, et al.
Publicado: (2022)

Comparison of high throughput RNA sequences between Babesia bigemina and Babesia bovis revealed consistent differential gene expression that is required for the Babesia life cycle in the vertebrate and invertebrate hosts
por: Capelli-Peixoto, Janaina, et al.
Publicado: (2022)

Babesia ovis secreted antigen-1 is a diagnostic marker during the active Babesia ovis infections in sheep
por: Sevinc, Ferda, et al.
Publicado: (2023)

Sensitive Immunoassay Detection of Plasmodium Lactate Dehydrogenase by Inductively Coupled Plasma Mass Spectrometry
por: Mu, Jianbing, et al.
Publicado: (2021)

Lactate dehydrogenase predicts disease progression outcome in COVID-19 patients treated with Azvudine
por: Mao, Manyun, et al.
Publicado: (2023)

Stimulation of metacyclogenesis in Leishmania (Mundinia) orientalis for mass production of metacyclic promastigotes
por: Chanmol, Wetpisit, et al.
Publicado: (2022)

The MEP pathway in Babesia orientalis apicoplast, a potential target for anti-babesiosis drug development
por: He, Lan, et al.
Publicado: (2018)

Identification of a novel thrombospondin-related anonymous protein (BoTRAP2) from Babesia orientalis
por: Zhan, Xueyan, et al.
Publicado: (2019)

Molecular Cloning and Characterization of Babesia orientalis Rhoptry Neck 2 BoRON2 Protein
por: Malobi, Ngabu, et al.
Publicado: (2017)

Whole genome sequence and diversity in multigene families of Babesia ovis
por: Yamagishi, Junya, et al.
Publicado: (2023)

Lessons Learned for Pathogenesis, Immunology, and Disease of Erythrocytic Parasites: Plasmodium and Babesia
por: Djokic, Vitomir, et al.
Publicado: (2021)

The Cross-Species Immunity During Acute Babesia Co-Infection in Mice
por: Zafar, Iqra, et al.
Publicado: (2022)

Babesia microti Infection Inhibits Melanoma Growth by Activating Macrophages in Mice
por: Shu, Xiang, et al.
Publicado: (2022)

Diagnostic accuracy and limit of detection of ten malaria parasite lactate dehydrogenase-based rapid tests for Plasmodium knowlesi and P. falciparum
por: Tan, Angelica F., et al.
Publicado: (2022)

A Novel Thioredoxin-Like Protein of Babesia microti Involved in Parasite Pathogenicity
por: Piao, Xianyu, et al.
Publicado: (2022)

Serum metabolomic profiles in BALB/c mice induced by Babesia microti infection
por: Shen, Liang, et al.
Publicado: (2023)

Integrative Transcriptomics and Proteomics Analyses to Reveal the Developmental Regulation of Metorchis orientalis: A Neglected Trematode With Potential Carcinogenic Implications
por: Gao, Jun-Feng, et al.
Publicado: (2021)

Establishment and Application of an Indirect Enzyme-Linked Immunosorbent Assay for Measuring GPI-Anchored Protein 52 (P52) Antibodies in Babesia gibsoni-Infected Dogs
por: Liu, Qin, et al.
Publicado: (2022)

Babesia microti Confers Macrophage-Based Cross-Protective Immunity Against Murine Malaria
por: Efstratiou, Artemis, et al.
Publicado: (2020)

Integration of DNA Repair, Antigenic Variation, Cytoadhesion, and Chance in Babesia Survival: A Perspective
por: Allred, David R.
Publicado: (2022)

Vitellogenin-2 Accumulation in the Fat Body and Hemolymph of Babesia-Infected Haemaphysalis longicornis Ticks
por: Kuniyori, Maki, et al.
Publicado: (2022)

A novel Babesia orientalis 135-kilodalton spherical body protein like: identification of its secretion into cytoplasm of infected erythrocytes
por: Guo, Jiaying, et al.
Publicado: (2018)

Phosphatidylinositol 4-kinase is a viable target for the radical cure of Babesia microti infection in immunocompromised hosts
por: Ji, Shengwei, et al.
Publicado: (2022)

Epitope profiling of monoclonal antibodies to the immunodominant antigen BmGPI12 of the human pathogen Babesia microti
por: Chand, Meenal, et al.
Publicado: (2022)

Identification and molecular characterization of a novel Babesia orientalis thrombospondin-related anonymous protein (BoTRAP1)
por: Yu, Long, et al.
Publicado: (2018)

Anti-parasitic drug discovery against Babesia microti by natural compounds: an extensive computational drug design approach
por: Akash, Shopnil, et al.
Publicado: (2023)

The Tick Microbiota Dysbiosis Promote Tick-Borne Pathogen Transstadial Transmission in a Babesia microti–Infected Mouse Model
por: Wei, Nana, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_aunjjiavso5713ngv5ba1t3muj