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Systematic review of human post‐mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease

AIMS: Reactive astrocytes in Alzheimer's disease (AD) have traditionally been demonstrated by increased glial fibrillary acidic protein (GFAP) immunoreactivity; however, astrocyte reaction is a complex and heterogeneous phenomenon involving multiple astrocyte functions beyond cytoskeletal remod...

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Detalles Bibliográficos
Autores principales: Viejo, Lucía, Noori, Ayush, Merrill, Emily, Das, Sudeshna, Hyman, Bradley T., Serrano‐Pozo, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766893/
https://www.ncbi.nlm.nih.gov/pubmed/34297416
http://dx.doi.org/10.1111/nan.12753