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Rutaecarpine Inhibits Doxorubicin-Induced Oxidative Stress and Apoptosis by Activating AKT Signaling Pathway

Patients with cancer who receive doxorubicin (DOX) treatment can experience cardiac dysfunction, which can finally develop into heart failure. Oxidative stress is considered the most important mechanism for DOX-mediated cardiotoxicity. Rutaecarpine (Rut), a quinazolinocarboline alkaloid extracted fr...

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Detalles Bibliográficos
Autores principales:	Liao, Zi-Qi, Jiang, Yi-Nong, Su, Zhuo-Lin, Bi, Hai-Lian, Li, Jia-Tian, Li, Cheng-Lin, Yang, Xiao-Lei, Zhang, Ying, Xie, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766983/ https://www.ncbi.nlm.nih.gov/pubmed/35071368 http://dx.doi.org/10.3389/fcvm.2021.809689

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