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Disseminated tuberculosis with symptoms of decreased consciousness: A rare case in Indonesian male

BACKGROUND: Disseminated tuberculosis is a rare case that causes high mortality and morbidity. CASE PRESENTATION: A 59-year-old man with a glasgow coma scale of 12, cerebrospinal fluid was found to have dominant mononuclear, high protein level, low glucose level and shortness of breath. A chest X-ra...

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Detalles Bibliográficos
Autores principales: Fauzi, Alvian, Permatasari, Ariani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767272/
https://www.ncbi.nlm.nih.gov/pubmed/35079359
http://dx.doi.org/10.1016/j.amsu.2021.103209
Descripción
Sumario:BACKGROUND: Disseminated tuberculosis is a rare case that causes high mortality and morbidity. CASE PRESENTATION: A 59-year-old man with a glasgow coma scale of 12, cerebrospinal fluid was found to have dominant mononuclear, high protein level, low glucose level and shortness of breath. A chest X-ray revealed a right pleural effusion with infiltrates in both lung parenchyma and a pleural fluid adenosine deaminase (ADA) test showed 66.1 U/L. Thoracolumbar MRI revealed a compression fracture in the 6th thoracic vertebral body. The patient was given category 1 anti-tuberculosis drug (ATD) therapy plus streptomycin and dexamethasone and water seal drainage (WSD) was installed. The patient experienced improvement after taking ATD after 4 months in which the patient could stand and walk by using an object in front of him. DISCUSSION: Accurate and prompt diagnosis of disseminated tuberculosis minimizes patient's mortality and morbidity. Suspicion of tuberculosis can be raised if the patient is experiencing health problems in endemic tuberculosis. CONCLUSION: Disseminated tuberculosis (pulmonary tuberculosis, tuberculous pleurisy, tuberculous meningitis, and tuberculous spondylitis) can be managed properly using ATD category 1.