Cargando…

Contrastive learning of heart and lung sounds for label-efficient diagnosis

Data labeling is often the limiting step in machine learning because it requires time from trained experts. To address the limitation on labeled data, contrastive learning, among other unsupervised learning methods, leverages unlabeled data to learn representations of data. Here, we propose a contra...

Descripción completa

Detalles Bibliográficos
Autores principales: Soni, Pratham N., Shi, Siyu, Sriram, Pranav R., Ng, Andrew Y., Rajpurkar, Pranav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767307/
https://www.ncbi.nlm.nih.gov/pubmed/35079716
http://dx.doi.org/10.1016/j.patter.2021.100400
_version_ 1784634708452179968
author Soni, Pratham N.
Shi, Siyu
Sriram, Pranav R.
Ng, Andrew Y.
Rajpurkar, Pranav
author_facet Soni, Pratham N.
Shi, Siyu
Sriram, Pranav R.
Ng, Andrew Y.
Rajpurkar, Pranav
author_sort Soni, Pratham N.
collection PubMed
description Data labeling is often the limiting step in machine learning because it requires time from trained experts. To address the limitation on labeled data, contrastive learning, among other unsupervised learning methods, leverages unlabeled data to learn representations of data. Here, we propose a contrastive learning framework that utilizes metadata for selecting positive and negative pairs when training on unlabeled data. We demonstrate its application in the healthcare domain on heart and lung sound recordings. The increasing availability of heart and lung sound recordings due to adoption of digital stethoscopes lends itself as an opportunity to demonstrate the application of our contrastive learning method. Compared to contrastive learning with augmentations, the contrastive learning model leveraging metadata for pair selection utilizes clinical information associated with lung and heart sound recordings. This approach uses shared context of the recordings on the patient level using clinical information including age, sex, weight, location of sounds, etc. We show improvement in downstream tasks for diagnosing heart and lung sounds when leveraging patient-specific representations in selecting positive and negative pairs. This study paves the path for medical applications of contrastive learning that leverage clinical information. We have made our code available here: https://github.com/stanfordmlgroup/selfsupervised-lungandheartsounds.
format Online
Article
Text
id pubmed-8767307
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-87673072022-01-24 Contrastive learning of heart and lung sounds for label-efficient diagnosis Soni, Pratham N. Shi, Siyu Sriram, Pranav R. Ng, Andrew Y. Rajpurkar, Pranav Patterns (N Y) Article Data labeling is often the limiting step in machine learning because it requires time from trained experts. To address the limitation on labeled data, contrastive learning, among other unsupervised learning methods, leverages unlabeled data to learn representations of data. Here, we propose a contrastive learning framework that utilizes metadata for selecting positive and negative pairs when training on unlabeled data. We demonstrate its application in the healthcare domain on heart and lung sound recordings. The increasing availability of heart and lung sound recordings due to adoption of digital stethoscopes lends itself as an opportunity to demonstrate the application of our contrastive learning method. Compared to contrastive learning with augmentations, the contrastive learning model leveraging metadata for pair selection utilizes clinical information associated with lung and heart sound recordings. This approach uses shared context of the recordings on the patient level using clinical information including age, sex, weight, location of sounds, etc. We show improvement in downstream tasks for diagnosing heart and lung sounds when leveraging patient-specific representations in selecting positive and negative pairs. This study paves the path for medical applications of contrastive learning that leverage clinical information. We have made our code available here: https://github.com/stanfordmlgroup/selfsupervised-lungandheartsounds. Elsevier 2021-12-07 /pmc/articles/PMC8767307/ /pubmed/35079716 http://dx.doi.org/10.1016/j.patter.2021.100400 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Soni, Pratham N.
Shi, Siyu
Sriram, Pranav R.
Ng, Andrew Y.
Rajpurkar, Pranav
Contrastive learning of heart and lung sounds for label-efficient diagnosis
title Contrastive learning of heart and lung sounds for label-efficient diagnosis
title_full Contrastive learning of heart and lung sounds for label-efficient diagnosis
title_fullStr Contrastive learning of heart and lung sounds for label-efficient diagnosis
title_full_unstemmed Contrastive learning of heart and lung sounds for label-efficient diagnosis
title_short Contrastive learning of heart and lung sounds for label-efficient diagnosis
title_sort contrastive learning of heart and lung sounds for label-efficient diagnosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767307/
https://www.ncbi.nlm.nih.gov/pubmed/35079716
http://dx.doi.org/10.1016/j.patter.2021.100400
work_keys_str_mv AT soniprathamn contrastivelearningofheartandlungsoundsforlabelefficientdiagnosis
AT shisiyu contrastivelearningofheartandlungsoundsforlabelefficientdiagnosis
AT srirampranavr contrastivelearningofheartandlungsoundsforlabelefficientdiagnosis
AT ngandrewy contrastivelearningofheartandlungsoundsforlabelefficientdiagnosis
AT rajpurkarpranav contrastivelearningofheartandlungsoundsforlabelefficientdiagnosis