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Liquiritin Alleviates Depression-Like Behavior in CUMS Mice by Inhibiting Oxidative Stress and NLRP3 Inflammasome in Hippocampus

OBJECTIVE: Central inflammation is generally accepted to be involved in the pathology of depression. We investigated whether liquiritin exerts antidepressant effects by inhibiting central NLRP3 inflammasomes. RESULTS: The behavioral despair model and chronic unpredictable mild stress (CUMS) model in...

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Detalles Bibliográficos
Autores principales: Liu, Chang, Yuan, Dai, Zhang, Chi, Tao, Ye, Meng, Ying, Jin, Mengli, Song, Wu, Wang, Bingmei, Wei, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767389/
https://www.ncbi.nlm.nih.gov/pubmed/35069768
http://dx.doi.org/10.1155/2022/7558825