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Oxidative Stress Aggravates Apoptosis of Nucleus Pulposus Cells through m(6)A Modification of MAT2A Pre-mRNA by METTL16

The process of intervertebral disc degeneration (IVDD) is complex, and its mechanism is considered multifactorial. Apoptosis of oxidative stressed nucleus pulposus cells (NPCs) should be a fundamental element in the pathogenesis of IVDD. In our pilot study, we found that the expression of MAT2A decr...

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Detalles Bibliográficos
Autores principales:	Chen, Peng-Bo, Shi, Gui-Xun, Liu, Tao, Li, Bo, Jiang, Sheng-Dan, Zheng, Xin-Feng, Jiang, Lei-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767407/ https://www.ncbi.nlm.nih.gov/pubmed/35069973 http://dx.doi.org/10.1155/2022/4036274

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