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Anion binding to a cationic europium(iii) probe enables the first real-time assay of heparan sulfotransferase activity
Sulfotransferases constitute a ubiquitous class of enzymes which are poorly understood due to the lack of a convenient tool for screening their activity. These enzymes use the anion PAPS (adenosine-3′-phosphate-5′-phosphosulfate) as a donor for a broad range of acceptor substrates, including carbohy...
| Auteurs principaux: | , , , , , , , , |
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| Format: | Online Article Texte |
| Langue: | English |
| Publié: |
The Royal Society of Chemistry
2021
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| Sujets: | |
| Accès en ligne: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767414/ https://www.ncbi.nlm.nih.gov/pubmed/34951618 http://dx.doi.org/10.1039/d1ob02071d |