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The thymic microenvironment gradually modulates the phenotype of thymus‐homing peripheral conventional dendritic cells
BACKGROUND & AIMS: Thymic conventional dendritic cells (t‑DCs) are crucial for the development of T cells. A substantial fraction of t‑DCs originates extrathymically and migrates to the thymus. Here, these cells contribute to key processes of central tolerance like the clonal deletion of self‑re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767516/ https://www.ncbi.nlm.nih.gov/pubmed/34748687 http://dx.doi.org/10.1002/iid3.559 |