Radiosynthesis of a novel antisense imaging probe targeting LncRNA HOTAIR in malignant glioma

BACKGROUND: Long non-coding RNA (LncRNA) HOTAIR was amplified and overexpressed in many human carcinomas, which could serve as a useful target for cancer early detection and treatment. The (99m)Tc radiolabeled antisense oligonucleotides (ASON) could visualize the expression of HOTAIR and provide a d...

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Detalles Bibliográficos
Autores principales: Ren, Jiongyu, Zhang, Xiyuan, Cao, Jiang, Tian, Jiali, Luo, Jin, Yu, Yaping, Wang, Fengkui, Zhao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767688/
https://www.ncbi.nlm.nih.gov/pubmed/35042456
http://dx.doi.org/10.1186/s12885-022-09170-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767688/
https://www.ncbi.nlm.nih.gov/pubmed/35042456
http://dx.doi.org/10.1186/s12885-022-09170-7

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