Cargando…
The Omicron (B.1.1.529) variant of SARS-CoV-2 binds to the hACE2 receptor more strongly and escapes the antibody response: Insights from structural and simulation data
As SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) continues to inflict chaos globally, a new variant officially known as B.1.1.529 was reported in South Africa and was found to harbor 30 mutations in the spike protein. It is too early to speculate on transmission and hospitalizations....
Autores principales: | Khan, Abbas, Waris, Hira, Rafique, Memoona, Suleman, Muhammad, Mohammad, Anwar, Ali, Syed Shujait, Khan, Taimoor, Waheed, Yasir, Liao, Chenguang, Wei, Dong-Qing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767976/ https://www.ncbi.nlm.nih.gov/pubmed/35063482 http://dx.doi.org/10.1016/j.ijbiomac.2022.01.059 |
Ejemplares similares
-
Blocking key mutated hotspot residues in the RBD of the omicron variant (B.1.1.529) with medicinal compounds to disrupt the RBD-hACE2 complex using molecular screening and simulation approaches
por: Khan, Abbas, et al.
Publicado: (2022) -
Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses
por: Dejnirattisai, Wanwisa, et al.
Publicado: (2021) -
SARS-CoV-2 Omicron variant (B.1.1.529): A concern with immune escape
por: Sanyaolu, Adekunle, et al.
Publicado: (2022) -
Targeting the RBD of Omicron Variant (B.1.1.529) with Medicinal Phytocompounds to Abrogate the Binding of Spike Glycoprotein with the hACE2 Using Computational Molecular Search and Simulation Approach
por: Hakami, Abdulrahim R.
Publicado: (2022) -
SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses
por: Dejnirattisai, Wanwisa, et al.
Publicado: (2022)