Cargando…

Mediastinal ectopic parathyroid adenomas: diagnostic and therapeutic challenge

INTRODUCTION: Mediastinal parathyroid adenomas are a rare condition. AIM: Analysis of epidemiological data, clinical manifestation of mediastinal parathyroid adenoma (MPA), including imaging modalities, and therapeutic approach to this condition. MATERIAL AND METHODS: A retrospective study of docume...

Descripción completa

Detalles Bibliográficos
Autores principales: El Hammoumi, Massine, Kamdem, Marius, Amraoui, Mouad, Bhairis, Mohamed, Kabiri, el Hassane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768862/
https://www.ncbi.nlm.nih.gov/pubmed/35079264
http://dx.doi.org/10.5114/kitp.2021.112189
_version_ 1784635012950261760
author El Hammoumi, Massine
Kamdem, Marius
Amraoui, Mouad
Bhairis, Mohamed
Kabiri, el Hassane
author_facet El Hammoumi, Massine
Kamdem, Marius
Amraoui, Mouad
Bhairis, Mohamed
Kabiri, el Hassane
author_sort El Hammoumi, Massine
collection PubMed
description INTRODUCTION: Mediastinal parathyroid adenomas are a rare condition. AIM: Analysis of epidemiological data, clinical manifestation of mediastinal parathyroid adenoma (MPA), including imaging modalities, and therapeutic approach to this condition. MATERIAL AND METHODS: A retrospective study of documented cases of mediastinal parathyroid adenoma that were managed at our Department of Thoracic Surgery of the Military Teaching Hospital Mohammed V, between January 2010 and December 2019. RESULTS: During a 9-year period in our department, 21 documented cases of MPA were treated surgically. Patients ranged in age from 20 to 69 years, with a mean age of 45 years, and there was no gender predominance. The most frequently reported manifestations were osteoarticular, with bone pain in 66.6% (14/21), pathological fractures in 28.5% (6/21), and osteoporosis in 23.8% (5/21). Cervical ultrasound, MIBI scintigraphy and cervico-thoracic computed tomography scan were performed respectively in 28.5% (n = 06/21), in 47.6% (n = 10/21) and 100% (n = 21), and allowed positive diagnosis of MPA. All patients benefited from resection surgery, through a classical transverse cervicotomy which was extended in some cases to the manubrium, and in only one case treated with thoracotomy. CONCLUSIONS: Management of mediastinal parathyroid adenoma is based on the diagnosis imaging assessment step, usually by MIBI scintigraphy. Surgical ablation is a radical treatment. Peroperative hormonal evaluation is mainly recommended.
format Online
Article
Text
id pubmed-8768862
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Termedia Publishing House
record_format MEDLINE/PubMed
spelling pubmed-87688622022-01-24 Mediastinal ectopic parathyroid adenomas: diagnostic and therapeutic challenge El Hammoumi, Massine Kamdem, Marius Amraoui, Mouad Bhairis, Mohamed Kabiri, el Hassane Kardiochir Torakochirurgia Pol Original Article INTRODUCTION: Mediastinal parathyroid adenomas are a rare condition. AIM: Analysis of epidemiological data, clinical manifestation of mediastinal parathyroid adenoma (MPA), including imaging modalities, and therapeutic approach to this condition. MATERIAL AND METHODS: A retrospective study of documented cases of mediastinal parathyroid adenoma that were managed at our Department of Thoracic Surgery of the Military Teaching Hospital Mohammed V, between January 2010 and December 2019. RESULTS: During a 9-year period in our department, 21 documented cases of MPA were treated surgically. Patients ranged in age from 20 to 69 years, with a mean age of 45 years, and there was no gender predominance. The most frequently reported manifestations were osteoarticular, with bone pain in 66.6% (14/21), pathological fractures in 28.5% (6/21), and osteoporosis in 23.8% (5/21). Cervical ultrasound, MIBI scintigraphy and cervico-thoracic computed tomography scan were performed respectively in 28.5% (n = 06/21), in 47.6% (n = 10/21) and 100% (n = 21), and allowed positive diagnosis of MPA. All patients benefited from resection surgery, through a classical transverse cervicotomy which was extended in some cases to the manubrium, and in only one case treated with thoracotomy. CONCLUSIONS: Management of mediastinal parathyroid adenoma is based on the diagnosis imaging assessment step, usually by MIBI scintigraphy. Surgical ablation is a radical treatment. Peroperative hormonal evaluation is mainly recommended. Termedia Publishing House 2022-01-09 2021-12 /pmc/articles/PMC8768862/ /pubmed/35079264 http://dx.doi.org/10.5114/kitp.2021.112189 Text en Copyright: © 2021 Polish Society of Cardiothoracic Surgeons (Polskie Towarzystwo KardioTorakochirurgów) and the editors of the Polish Journal of Cardio-Thoracic Surgery (Kardiochirurgia i Torakochirurgia Polska) https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Article
El Hammoumi, Massine
Kamdem, Marius
Amraoui, Mouad
Bhairis, Mohamed
Kabiri, el Hassane
Mediastinal ectopic parathyroid adenomas: diagnostic and therapeutic challenge
title Mediastinal ectopic parathyroid adenomas: diagnostic and therapeutic challenge
title_full Mediastinal ectopic parathyroid adenomas: diagnostic and therapeutic challenge
title_fullStr Mediastinal ectopic parathyroid adenomas: diagnostic and therapeutic challenge
title_full_unstemmed Mediastinal ectopic parathyroid adenomas: diagnostic and therapeutic challenge
title_short Mediastinal ectopic parathyroid adenomas: diagnostic and therapeutic challenge
title_sort mediastinal ectopic parathyroid adenomas: diagnostic and therapeutic challenge
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768862/
https://www.ncbi.nlm.nih.gov/pubmed/35079264
http://dx.doi.org/10.5114/kitp.2021.112189
work_keys_str_mv AT elhammoumimassine mediastinalectopicparathyroidadenomasdiagnosticandtherapeuticchallenge
AT kamdemmarius mediastinalectopicparathyroidadenomasdiagnosticandtherapeuticchallenge
AT amraouimouad mediastinalectopicparathyroidadenomasdiagnosticandtherapeuticchallenge
AT bhairismohamed mediastinalectopicparathyroidadenomasdiagnosticandtherapeuticchallenge
AT kabirielhassane mediastinalectopicparathyroidadenomasdiagnosticandtherapeuticchallenge