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Novel case of takotsubo cardiomyopathy following COVID-19 vaccination
We present an unusual case of takotsubo cardiomyopathy (TTC) following administration of the second dose of the DNA ChadOX1 nCOV-19 (AZD122) vaccination. This woman in her early 50s presented to the emergency department 8 days following her vaccine with central chest pain. Initial investigations rev...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768865/ https://www.ncbi.nlm.nih.gov/pubmed/35042734 http://dx.doi.org/10.1136/bcr-2021-247291 |
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author | Stewart, Caitlin Gamble, David T Dawson, Dana |
author_facet | Stewart, Caitlin Gamble, David T Dawson, Dana |
author_sort | Stewart, Caitlin |
collection | PubMed |
description | We present an unusual case of takotsubo cardiomyopathy (TTC) following administration of the second dose of the DNA ChadOX1 nCOV-19 (AZD122) vaccination. This woman in her early 50s presented to the emergency department 8 days following her vaccine with central chest pain. Initial investigations revealed a raised troponin and evolving T wave inversion on ECG. Acute coronary syndrome management was commenced. Further investigations revealed non-obstructive coronary arteries on coronary angiography and imaging revealed hypokinesia of the anterior and anterior-septal walls in the apex and midcavity level, myocardial oedema and no infarction, all in keeping with TTC. Given the large-scale roll out of vaccinations during the COVID-19 pandemic better understanding of potential adverse events is essential. This is the first case report of TTC following a second dose of the DNA ChadOX1 nCOV-19 (AZD122) vaccination. |
format | Online Article Text |
id | pubmed-8768865 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-87688652022-02-04 Novel case of takotsubo cardiomyopathy following COVID-19 vaccination Stewart, Caitlin Gamble, David T Dawson, Dana BMJ Case Rep Case Report We present an unusual case of takotsubo cardiomyopathy (TTC) following administration of the second dose of the DNA ChadOX1 nCOV-19 (AZD122) vaccination. This woman in her early 50s presented to the emergency department 8 days following her vaccine with central chest pain. Initial investigations revealed a raised troponin and evolving T wave inversion on ECG. Acute coronary syndrome management was commenced. Further investigations revealed non-obstructive coronary arteries on coronary angiography and imaging revealed hypokinesia of the anterior and anterior-septal walls in the apex and midcavity level, myocardial oedema and no infarction, all in keeping with TTC. Given the large-scale roll out of vaccinations during the COVID-19 pandemic better understanding of potential adverse events is essential. This is the first case report of TTC following a second dose of the DNA ChadOX1 nCOV-19 (AZD122) vaccination. BMJ Publishing Group 2022-01-18 /pmc/articles/PMC8768865/ /pubmed/35042734 http://dx.doi.org/10.1136/bcr-2021-247291 Text en © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for personal use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained. |
spellingShingle | Case Report Stewart, Caitlin Gamble, David T Dawson, Dana Novel case of takotsubo cardiomyopathy following COVID-19 vaccination |
title | Novel case of takotsubo cardiomyopathy following COVID-19 vaccination |
title_full | Novel case of takotsubo cardiomyopathy following COVID-19 vaccination |
title_fullStr | Novel case of takotsubo cardiomyopathy following COVID-19 vaccination |
title_full_unstemmed | Novel case of takotsubo cardiomyopathy following COVID-19 vaccination |
title_short | Novel case of takotsubo cardiomyopathy following COVID-19 vaccination |
title_sort | novel case of takotsubo cardiomyopathy following covid-19 vaccination |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768865/ https://www.ncbi.nlm.nih.gov/pubmed/35042734 http://dx.doi.org/10.1136/bcr-2021-247291 |
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