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Novel case of takotsubo cardiomyopathy following COVID-19 vaccination

We present an unusual case of takotsubo cardiomyopathy (TTC) following administration of the second dose of the DNA ChadOX1 nCOV-19 (AZD122) vaccination. This woman in her early 50s presented to the emergency department 8 days following her vaccine with central chest pain. Initial investigations rev...

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Detalles Bibliográficos
Autores principales: Stewart, Caitlin, Gamble, David T, Dawson, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768865/
https://www.ncbi.nlm.nih.gov/pubmed/35042734
http://dx.doi.org/10.1136/bcr-2021-247291
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author Stewart, Caitlin
Gamble, David T
Dawson, Dana
author_facet Stewart, Caitlin
Gamble, David T
Dawson, Dana
author_sort Stewart, Caitlin
collection PubMed
description We present an unusual case of takotsubo cardiomyopathy (TTC) following administration of the second dose of the DNA ChadOX1 nCOV-19 (AZD122) vaccination. This woman in her early 50s presented to the emergency department 8 days following her vaccine with central chest pain. Initial investigations revealed a raised troponin and evolving T wave inversion on ECG. Acute coronary syndrome management was commenced. Further investigations revealed non-obstructive coronary arteries on coronary angiography and imaging revealed hypokinesia of the anterior and anterior-septal walls in the apex and midcavity level, myocardial oedema and no infarction, all in keeping with TTC. Given the large-scale roll out of vaccinations during the COVID-19 pandemic better understanding of potential adverse events is essential. This is the first case report of TTC following a second dose of the DNA ChadOX1 nCOV-19 (AZD122) vaccination.
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spelling pubmed-87688652022-02-04 Novel case of takotsubo cardiomyopathy following COVID-19 vaccination Stewart, Caitlin Gamble, David T Dawson, Dana BMJ Case Rep Case Report We present an unusual case of takotsubo cardiomyopathy (TTC) following administration of the second dose of the DNA ChadOX1 nCOV-19 (AZD122) vaccination. This woman in her early 50s presented to the emergency department 8 days following her vaccine with central chest pain. Initial investigations revealed a raised troponin and evolving T wave inversion on ECG. Acute coronary syndrome management was commenced. Further investigations revealed non-obstructive coronary arteries on coronary angiography and imaging revealed hypokinesia of the anterior and anterior-septal walls in the apex and midcavity level, myocardial oedema and no infarction, all in keeping with TTC. Given the large-scale roll out of vaccinations during the COVID-19 pandemic better understanding of potential adverse events is essential. This is the first case report of TTC following a second dose of the DNA ChadOX1 nCOV-19 (AZD122) vaccination. BMJ Publishing Group 2022-01-18 /pmc/articles/PMC8768865/ /pubmed/35042734 http://dx.doi.org/10.1136/bcr-2021-247291 Text en © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for personal use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.
spellingShingle Case Report
Stewart, Caitlin
Gamble, David T
Dawson, Dana
Novel case of takotsubo cardiomyopathy following COVID-19 vaccination
title Novel case of takotsubo cardiomyopathy following COVID-19 vaccination
title_full Novel case of takotsubo cardiomyopathy following COVID-19 vaccination
title_fullStr Novel case of takotsubo cardiomyopathy following COVID-19 vaccination
title_full_unstemmed Novel case of takotsubo cardiomyopathy following COVID-19 vaccination
title_short Novel case of takotsubo cardiomyopathy following COVID-19 vaccination
title_sort novel case of takotsubo cardiomyopathy following covid-19 vaccination
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768865/
https://www.ncbi.nlm.nih.gov/pubmed/35042734
http://dx.doi.org/10.1136/bcr-2021-247291
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