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COVID-19 in two children with new-onset diabetes: case reports
Delayed diagnosis, low socioeconomic status and infection have been associated with diabetic ketoacidosis (DKA) at type 1 diabetes mellitus presentation. A teenager from a low socioeconomic status family, with longstanding weight loss, polyphagia, polyuria, vomiting and abdominal pain, attended the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768866/ https://www.ncbi.nlm.nih.gov/pubmed/35042735 http://dx.doi.org/10.1136/bcr-2021-247309 |
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author | Lança, Ana Rodrigues, Cláudia Diamantino, Catarina Fitas, Ana Laura |
author_facet | Lança, Ana Rodrigues, Cláudia Diamantino, Catarina Fitas, Ana Laura |
author_sort | Lança, Ana |
collection | PubMed |
description | Delayed diagnosis, low socioeconomic status and infection have been associated with diabetic ketoacidosis (DKA) at type 1 diabetes mellitus presentation. A teenager from a low socioeconomic status family, with longstanding weight loss, polyphagia, polyuria, vomiting and abdominal pain, attended the emergency department, also complaining of anosmia and odynophagia. He was diagnosed with COVID-19 and new-onset DKA. The second child had 2 weeks of diabetes symptoms and was admitted with new-onset mild DKA. SARS-CoV-2 RT-PCR test was positive, although asymptomatic. Persistent hyperglycaemia with high insulin requirements was a common feature to both patients. Both cases support that SARS-CoV-2 may have an association with rapidly increasing insulin daily needs. In case one, not only fear of COVID-19 delayed hospital attendance but also the setting of a low socioeconomic status family appears to have enhanced the risk for late diagnosis and challenging disease management. |
format | Online Article Text |
id | pubmed-8768866 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-87688662022-02-04 COVID-19 in two children with new-onset diabetes: case reports Lança, Ana Rodrigues, Cláudia Diamantino, Catarina Fitas, Ana Laura BMJ Case Rep Case Report Delayed diagnosis, low socioeconomic status and infection have been associated with diabetic ketoacidosis (DKA) at type 1 diabetes mellitus presentation. A teenager from a low socioeconomic status family, with longstanding weight loss, polyphagia, polyuria, vomiting and abdominal pain, attended the emergency department, also complaining of anosmia and odynophagia. He was diagnosed with COVID-19 and new-onset DKA. The second child had 2 weeks of diabetes symptoms and was admitted with new-onset mild DKA. SARS-CoV-2 RT-PCR test was positive, although asymptomatic. Persistent hyperglycaemia with high insulin requirements was a common feature to both patients. Both cases support that SARS-CoV-2 may have an association with rapidly increasing insulin daily needs. In case one, not only fear of COVID-19 delayed hospital attendance but also the setting of a low socioeconomic status family appears to have enhanced the risk for late diagnosis and challenging disease management. BMJ Publishing Group 2022-01-18 /pmc/articles/PMC8768866/ /pubmed/35042735 http://dx.doi.org/10.1136/bcr-2021-247309 Text en © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for personal use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained. |
spellingShingle | Case Report Lança, Ana Rodrigues, Cláudia Diamantino, Catarina Fitas, Ana Laura COVID-19 in two children with new-onset diabetes: case reports |
title | COVID-19 in two children with new-onset diabetes: case reports |
title_full | COVID-19 in two children with new-onset diabetes: case reports |
title_fullStr | COVID-19 in two children with new-onset diabetes: case reports |
title_full_unstemmed | COVID-19 in two children with new-onset diabetes: case reports |
title_short | COVID-19 in two children with new-onset diabetes: case reports |
title_sort | covid-19 in two children with new-onset diabetes: case reports |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768866/ https://www.ncbi.nlm.nih.gov/pubmed/35042735 http://dx.doi.org/10.1136/bcr-2021-247309 |
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