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Median Nerve Affection in Hypertensive Patients with and without Diabetes High-Resolution Ultrasound Assessment

PURPOSE: Diabetes is a documented risk factor for peripheral neuropathy. It was reported that associated hypertension could increase this risk. The present study aimed to assess the effect of hypertension and diabetes on median nerve using high-resolution ultrasound. METHODS: The study includes 50 h...

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Autores principales: Esmat, Ahmed, Elshamy, Mahmoud I, Mohamed Zakaria, Doaa, Shady, Zakarya, Roshdy Mohamed, Eman, El-Khouly, Nashwa, Hassan, Marwa M, El-Senosy, Fatma M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769048/
https://www.ncbi.nlm.nih.gov/pubmed/35068936
http://dx.doi.org/10.2147/DMSO.S340111
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author Esmat, Ahmed
Elshamy, Mahmoud I
Mohamed Zakaria, Doaa
Shady, Zakarya
Roshdy Mohamed, Eman
El-Khouly, Nashwa
Hassan, Marwa M
El-Senosy, Fatma M
author_facet Esmat, Ahmed
Elshamy, Mahmoud I
Mohamed Zakaria, Doaa
Shady, Zakarya
Roshdy Mohamed, Eman
El-Khouly, Nashwa
Hassan, Marwa M
El-Senosy, Fatma M
author_sort Esmat, Ahmed
collection PubMed
description PURPOSE: Diabetes is a documented risk factor for peripheral neuropathy. It was reported that associated hypertension could increase this risk. The present study aimed to assess the effect of hypertension and diabetes on median nerve using high-resolution ultrasound. METHODS: The study includes 50 hypertensive patients (HTN group), 50 diabetic patients (DM group), 50 patients with coexisting diabetes and hypertension (HTN + DM group) and 50 healthy controls. Median nerve affection in the studied groups was studied by vibration perception thresholds (VPT). The median nerve cross-sectional area was determined at the nerve cross-sectional area of the median nerve at the carpal tunnel by high-resolution ultrasound. Clinical symptoms were assessed using Toronto Clinical Severity Score (TCSS). RESULTS: There was significantly higher median nerve CSA in all patient groups in comparison to controls. HTN + DM group had significantly higher median nerve CSA when compared with DM group. Patients with peripheral neuropathy in HTN + DM and DM groups had significantly higher median nerve CSA than patients without. Using ROC curve analysis, it was shown that median CSA could successfully distinguish patients with peripheral neuropathy from patients without in HTN + DM group [AUC (95% CI): 0.71 (0.54–0.89)] and in DM group [AUC (95% CI): 0.86 (0.72–0.99)]. CONCLUSION: Hypertensive patients with and without diabetes have significantly higher median nerve CSA when compared with controls.
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spelling pubmed-87690482022-01-20 Median Nerve Affection in Hypertensive Patients with and without Diabetes High-Resolution Ultrasound Assessment Esmat, Ahmed Elshamy, Mahmoud I Mohamed Zakaria, Doaa Shady, Zakarya Roshdy Mohamed, Eman El-Khouly, Nashwa Hassan, Marwa M El-Senosy, Fatma M Diabetes Metab Syndr Obes Original Research PURPOSE: Diabetes is a documented risk factor for peripheral neuropathy. It was reported that associated hypertension could increase this risk. The present study aimed to assess the effect of hypertension and diabetes on median nerve using high-resolution ultrasound. METHODS: The study includes 50 hypertensive patients (HTN group), 50 diabetic patients (DM group), 50 patients with coexisting diabetes and hypertension (HTN + DM group) and 50 healthy controls. Median nerve affection in the studied groups was studied by vibration perception thresholds (VPT). The median nerve cross-sectional area was determined at the nerve cross-sectional area of the median nerve at the carpal tunnel by high-resolution ultrasound. Clinical symptoms were assessed using Toronto Clinical Severity Score (TCSS). RESULTS: There was significantly higher median nerve CSA in all patient groups in comparison to controls. HTN + DM group had significantly higher median nerve CSA when compared with DM group. Patients with peripheral neuropathy in HTN + DM and DM groups had significantly higher median nerve CSA than patients without. Using ROC curve analysis, it was shown that median CSA could successfully distinguish patients with peripheral neuropathy from patients without in HTN + DM group [AUC (95% CI): 0.71 (0.54–0.89)] and in DM group [AUC (95% CI): 0.86 (0.72–0.99)]. CONCLUSION: Hypertensive patients with and without diabetes have significantly higher median nerve CSA when compared with controls. Dove 2022-01-15 /pmc/articles/PMC8769048/ /pubmed/35068936 http://dx.doi.org/10.2147/DMSO.S340111 Text en © 2022 Esmat et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Esmat, Ahmed
Elshamy, Mahmoud I
Mohamed Zakaria, Doaa
Shady, Zakarya
Roshdy Mohamed, Eman
El-Khouly, Nashwa
Hassan, Marwa M
El-Senosy, Fatma M
Median Nerve Affection in Hypertensive Patients with and without Diabetes High-Resolution Ultrasound Assessment
title Median Nerve Affection in Hypertensive Patients with and without Diabetes High-Resolution Ultrasound Assessment
title_full Median Nerve Affection in Hypertensive Patients with and without Diabetes High-Resolution Ultrasound Assessment
title_fullStr Median Nerve Affection in Hypertensive Patients with and without Diabetes High-Resolution Ultrasound Assessment
title_full_unstemmed Median Nerve Affection in Hypertensive Patients with and without Diabetes High-Resolution Ultrasound Assessment
title_short Median Nerve Affection in Hypertensive Patients with and without Diabetes High-Resolution Ultrasound Assessment
title_sort median nerve affection in hypertensive patients with and without diabetes high-resolution ultrasound assessment
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769048/
https://www.ncbi.nlm.nih.gov/pubmed/35068936
http://dx.doi.org/10.2147/DMSO.S340111
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