The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

Background: The pharmacogenetic effect on cardiovascular disease reduction in response to statin treatment has only been assessed in small studies. In a pharmacogenetic genome wide association study (GWAS) analysis within the Genomic Investigation of Statin Therapy (GIST) consortium, we investigated...

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Detalles Bibliográficos
Autores principales: Trompet, Stella, Postmus, Iris, Warren, Helen R., Noordam, Raymond, Smit, Roelof A. J., Theusch, Elizabeth, Li, Xiaohui, Arsenault, Benoit, Chasman, Daniel I., Hitman, Graham A., Munroe, Patricia B., Rotter, Jerome I., Psaty, Bruce M., Caulfield, Mark J., Krauss, Ron M., Cupples, Adrienne L., Jukema, Wouter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769168/
https://www.ncbi.nlm.nih.gov/pubmed/35069183
http://dx.doi.org/10.3389/fphar.2021.679857

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