A standardised Phase III clinical trial framework to assess therapeutic interventions for Lassa fever

BACKGROUND: Only one recommendation currently exists for the treatment of Lassa fever (LF), which is ribavirin administered in conjunction with supportive care. This recommendation is primarily based on evidence generated from a single clinical trial that was conducted more than 30 years ago–the met...

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Detalles Bibliográficos
Autores principales: Olayinka, Adebola Tolulope, Bourner, Josephine, Akpede, George O., Okoeguale, Joseph, Abejegah, Chukwuyem, Ajayi, Nnennaya A., Akude, Christian, Ayodeji, Oluwafemi, Bausch, Daniel G., de Clerck, Hilde, Dan-Nwafor, Chioma, Dunning, Jake, Erameh, Cyril, Eze, Justus Ndulue, Formenty, Pierre, Gillesen, Annelies, Jalloh, Sulaiman, Jaspard, Marie, Jegede, Tolulope, Maikere, Jacob, Malvy, Denis, Ogbaini-Emovon, Ephraim, Ojo, Olalekan Ezekial, Okogbenin, Sylvanus, O’Neill, Kwame, Orji, Maria-Lauretta, Owhin, Sampson Omagbemi, Ramharter, Michael, Samuels, Robert J., Shehu, Nathan, Merson, Laura, Salam, Alex Paddy, Kayem, Nzelle Delphine, Horby, Peter, Ihekweazu, Chikwe, Olliaro, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769305/
https://www.ncbi.nlm.nih.gov/pubmed/34990453
http://dx.doi.org/10.1371/journal.pntd.0010089

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