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Cross-reactive and mono-reactive SARS-CoV-2 CD4+ T cells in prepandemic and COVID-19 convalescent individuals

Class II tetramer reagents for eleven common DR alleles and a DP allele prevalent in the world population were used to identify SARS-CoV-2 CD4+ T cell epitopes. A total of 112, 28 and 42 epitopes specific for Spike, Membrane and Nucleocapsid, respectively, with defined HLA-restriction were identifie...

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Detalles Bibliográficos
Autores principales:	Johansson, Alexandra M., Malhotra, Uma, Kim, Yeseul G., Gomez, Rebecca, Krist, Maxwell P., Wald, Anna, Koelle, David M., Kwok, William W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769337/ https://www.ncbi.nlm.nih.gov/pubmed/34965282 http://dx.doi.org/10.1371/journal.ppat.1010203

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