Large Cell Neuroendocrine Carcinoma in the Sinonasal Cavity with Large Intracranial Extension Treated with Endonasal Endoscopic and Transcranial Combined Surgery: A Case Report

Large cell neuroendocrine carcinoma (LCNEC) is a rare malignant tumor that typically arises in the lungs. It is especially rare in the sinonasal cavity, and treatment has not been established. In this study, we present the case of a 56-year-old woman with a large sinonasal LCNEC that extended into h...

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Autores principales: RAI, Yurie, NISHIOKA, Hiroshi, HARA, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769427/
https://www.ncbi.nlm.nih.gov/pubmed/35079508
http://dx.doi.org/10.2176/nmccrj.cr.2020-0424
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author RAI, Yurie
NISHIOKA, Hiroshi
HARA, Takayuki
author_facet RAI, Yurie
NISHIOKA, Hiroshi
HARA, Takayuki
author_sort RAI, Yurie
collection PubMed
description Large cell neuroendocrine carcinoma (LCNEC) is a rare malignant tumor that typically arises in the lungs. It is especially rare in the sinonasal cavity, and treatment has not been established. In this study, we present the case of a 56-year-old woman with a large sinonasal LCNEC that extended into her brain. We performed endonasal endoscopic and transcranial combined surgery followed by chemoradiation therapy. The combined surgery enabled us to approach and remove the extensive tumor from two different directions at one time less invasively. We have achieved good tumor control for 18 months so far.
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spelling pubmed-87694272022-01-24 Large Cell Neuroendocrine Carcinoma in the Sinonasal Cavity with Large Intracranial Extension Treated with Endonasal Endoscopic and Transcranial Combined Surgery: A Case Report RAI, Yurie NISHIOKA, Hiroshi HARA, Takayuki NMC Case Rep J Case Report Large cell neuroendocrine carcinoma (LCNEC) is a rare malignant tumor that typically arises in the lungs. It is especially rare in the sinonasal cavity, and treatment has not been established. In this study, we present the case of a 56-year-old woman with a large sinonasal LCNEC that extended into her brain. We performed endonasal endoscopic and transcranial combined surgery followed by chemoradiation therapy. The combined surgery enabled us to approach and remove the extensive tumor from two different directions at one time less invasively. We have achieved good tumor control for 18 months so far. The Japan Neurosurgical Society 2021-08-07 /pmc/articles/PMC8769427/ /pubmed/35079508 http://dx.doi.org/10.2176/nmccrj.cr.2020-0424 Text en © 2021 The Japan Neurosurgical Society https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Case Report
RAI, Yurie
NISHIOKA, Hiroshi
HARA, Takayuki
Large Cell Neuroendocrine Carcinoma in the Sinonasal Cavity with Large Intracranial Extension Treated with Endonasal Endoscopic and Transcranial Combined Surgery: A Case Report
title Large Cell Neuroendocrine Carcinoma in the Sinonasal Cavity with Large Intracranial Extension Treated with Endonasal Endoscopic and Transcranial Combined Surgery: A Case Report
title_full Large Cell Neuroendocrine Carcinoma in the Sinonasal Cavity with Large Intracranial Extension Treated with Endonasal Endoscopic and Transcranial Combined Surgery: A Case Report
title_fullStr Large Cell Neuroendocrine Carcinoma in the Sinonasal Cavity with Large Intracranial Extension Treated with Endonasal Endoscopic and Transcranial Combined Surgery: A Case Report
title_full_unstemmed Large Cell Neuroendocrine Carcinoma in the Sinonasal Cavity with Large Intracranial Extension Treated with Endonasal Endoscopic and Transcranial Combined Surgery: A Case Report
title_short Large Cell Neuroendocrine Carcinoma in the Sinonasal Cavity with Large Intracranial Extension Treated with Endonasal Endoscopic and Transcranial Combined Surgery: A Case Report
title_sort large cell neuroendocrine carcinoma in the sinonasal cavity with large intracranial extension treated with endonasal endoscopic and transcranial combined surgery: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769427/
https://www.ncbi.nlm.nih.gov/pubmed/35079508
http://dx.doi.org/10.2176/nmccrj.cr.2020-0424
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AT nishiokahiroshi largecellneuroendocrinecarcinomainthesinonasalcavitywithlargeintracranialextensiontreatedwithendonasalendoscopicandtranscranialcombinedsurgeryacasereport
AT haratakayuki largecellneuroendocrinecarcinomainthesinonasalcavitywithlargeintracranialextensiontreatedwithendonasalendoscopicandtranscranialcombinedsurgeryacasereport

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